Is Dietary Protein Intake Predictive of 1-Year Mortality in Dialysis Patients?

Murray, David P.; Young, Lufei; Waller, Jennifer L.; Wright, Stephanie; Colombo, Rhonda E; Baer, Stephanie L.; Spearman, Vanessa; García-Torres, Rosalía; Williams, Kori; Kheda, Mufaddal; Nahman, N. S.

doi:10.1016/j.amjms.2018.06.010

Cited by 12 publications

(2 citation statements)

References 36 publications

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“…Dialysis treatment is expected to improve nutritional status for patients with a more liberal protein prescription compared to the pre-dialysis stage [29][30][31]. However, dialysis treatment is cited to contribute to malnutrition burden [8], and newly dialyzing patients are at risk of the early mortality attributed to malnutrition as evidenced by diagnostic assessment of nutrition risk screening using SGA [32], low body mass index (BMI), low mid-arm muscle circumference (MAMC) [22,33,34], low albumin [20], low cholesterol levels [32], and reduced food intake [22,[33][34][35], as shown in Table 1.…”

Section: Development Of Malnutrition At the Time Of Hd Initiation And Indicators Of Poor Nutritional Statusmentioning

confidence: 99%

Understanding Development of Malnutrition in Hemodialysis Patients: A Narrative Review

et al. 2020

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Hemodialysis (HD) majorly represents the global treatment option for patients with chronic kidney disease stage 5, and, despite advances in dialysis technology, these patients face a high risk of morbidity and mortality from malnutrition. We aimed to provide a novel view that malnutrition susceptibility in the global HD community is either or both of iatrogenic and of non-iatrogenic origins. This categorization of malnutrition origin clearly describes the role of each factor in contributing to malnutrition. Low dialysis adequacy resulting in uremia and metabolic acidosis and dialysis membranes and techniques, which incur greater amino-acid losses, are identified modifiable iatrogenic factors of malnutrition. Dietary inadequacy as per suboptimal energy and protein intakes due to poor appetite status, low diet quality, high diet monotony index, and/or psychosocial and financial barriers are modifiable non-iatrogenic factors implicated in malnutrition in these patients. These factors should be included in a comprehensive nutritional assessment for malnutrition risk. Leveraging the point of origin of malnutrition in dialysis patients is crucial for healthcare practitioners to enable personalized patient care, as well as determine country-specific malnutrition treatment strategies.

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Section: Development Of Malnutrition At the Time Of Hd Initiation And Indicators Of Poor Nutritional Statusmentioning

confidence: 99%

Understanding Development of Malnutrition in Hemodialysis Patients: A Narrative Review

et al. 2020

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“…At the time of HD initiation, a patient presenting with malnutrition has a high mortality risk on the basis of low nutrition markers, such as geriatric nutritional risk index (GNRI) [ 20 ], subjective global assessment [ 21 ], low body mass index (BMI) [ 22 ], low serum levels of albumin [ 20 ] and cholesterol [ 21 ], and low food intake [ 23 ]. Among these parameters, we reported the clinical utility of GNRI as a relevant predictor for mortality in HD patients [ 20 ].…”

Section: Significance Of Malnutrition For Various Clinical Outcomes In Hd Patientsmentioning

confidence: 99%

Importance of Considering Malnutrition and Sarcopenia in Order to Improve the QOL of Elderly Hemodialysis Patients in Japan in the Era of 100-Year Life

Inaba

Okuno

Ohno³

2021

Nutrients

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In the current aging society of Japan, malnutrition and resultant sarcopenia have been widely identified as important symptomatic indicators of ill health and can cause impairments of longevity and quality of life in older individuals. Elderly individuals are recommended to have sufficient calorie and protein intake so as to enjoy a satisfactory quality of life, including maintaining activities of daily living in order to avoid emaciation and sarcopenia. The prevalence of emaciation and sarcopenia in elderly hemodialysis (HD) patients in Japan is higher than in non-HD elderly subjects due to the presence of malnutrition and sarcopenia associated with chronic kidney disease (CKD). Furthermore, comorbidities, such as diabetes and osteoporosis, induce malnutrition and sarcopenia in HD patients. This review presents findings regarding the mechanisms of the development of these early symptomatic conditions and their significance for impaired QOL and increased mortality in elderly HD patients.

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