2022
DOI: 10.1093/jmp/jhac030
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Is Aging a Disease? The Theoretical Definition of Aging in the Light of the Philosophy of Medicine

Abstract: In the philosophical debate on aging, it is common to raise the question of the theoretical definition of aging in terms of its possible characterization as a disease. Understanding aging as a disease seems to imply its medicalization, which has important practical consequences. In this paper, we analyze the question of whether aging is a disease by appealing to the concept of disease in the philosophy of medicine. As a result of this analysis, we argue that a pragmatist approach to the conception of disease i… Show more

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Cited by 7 publications
(2 citation statements)
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References 43 publications
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“…Aging has gone through evolving definitions over the years, such as "a persistent decline in the age-specific fitness components of an organism due to internal physiological deterioration" [2] or "a progressive loss of function accompanied by decreasing fertility and increasing mortality with advancing age" [3]. More recently, a consensus has been reached on framing aging as a "normal way of functioning in biology from a certain age onwards" [4]. For instance, aging in different organisms (especially mammals) has been initially proposed to encompass nine common features, including genomic instability, telomere shortening attrition, epigenetic alteration, deregulation of nutrient sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, alteration of intercellular communication, and loss of proteostasis [5].…”
Section: Introductionmentioning
confidence: 99%
“…Aging has gone through evolving definitions over the years, such as "a persistent decline in the age-specific fitness components of an organism due to internal physiological deterioration" [2] or "a progressive loss of function accompanied by decreasing fertility and increasing mortality with advancing age" [3]. More recently, a consensus has been reached on framing aging as a "normal way of functioning in biology from a certain age onwards" [4]. For instance, aging in different organisms (especially mammals) has been initially proposed to encompass nine common features, including genomic instability, telomere shortening attrition, epigenetic alteration, deregulation of nutrient sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, alteration of intercellular communication, and loss of proteostasis [5].…”
Section: Introductionmentioning
confidence: 99%
“…Therefore, we will simultaneously address all of them if we directly address aging. One of us is committed to a more general extension of this sort (Saborido & García-Barranquero, 2022). For a broader theoretical literature see, Bostrom, 2005;Caplan, 2005;de Winter, 2015;Hayflick, 2007;Schramme, 2013.…”
Section: Introductionmentioning
confidence: 99%