Irritant dermatitis due to prolonged contact with Oilatum PlusR

Loo, Wei Jing; Alexandroff, A.B.; Burrows, Natalie

doi:10.1046/j.1365-2133.2003.50891.x

Cited by 24 publications

(24 citation statements)

References 5 publications

(4 reference statements)

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“…The potential for a bath emollient to be ‘trapped’ in the skin flexures, anogenital area and inner thighs may have contributed to the distribution of the rash in our patients (note the classical sparing of the vault of the axillae). Such a distribution equates with that already described in cases of irritancy to Oilatum ® Plus 5–8 . This problem could be exacerbated if the bath product was not mixed thoroughly or if too much was added to the bath water.…”

Section: Discussionmentioning

confidence: 52%

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Flexural allergic contact dermatitis to benzalkonium chloride in antiseptic bath oil

2007

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Benzalkonium chloride (BAK) is an acknowledged irritant but has also been identified as a cause of allergic contact dermatitis. The antiseptic bath emollient Oilatum Plus (Stiefel, High Wycombe, U.K.) contains a relatively high concentration of 6% BAK. We describe six patients who presented with flexural eczema, particularly involving the anogenital area, who had a history of using Oilatum Plus. Patch testing showed all six to have a type 4 allergy to BAK as well as other allergens. Avoidance of Oilatum Plus led to a resolution of the flexural eczema in each case.

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Section: Discussionmentioning

confidence: 52%

“…All reactions were positive (+) at day 4 with a crescendo response. There have been several recent reports of irritant contact dermatitis to Oilatum ® Plus presenting with eczema in a flexural and anogenital distribution 5–8 . In this report we describe six patients who presented with a flexural eczematous rash.…”

Section: Discussionmentioning

confidence: 85%

Flexural allergic contact dermatitis to benzalkonium chloride in antiseptic bath oil

2007

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“…1 5 The concentration of benzalkonium chloride in Oilatum Plus is noted to be significantly higher than most antiseptic bath emollients, which possibly accounts for the acute irritant reactions. 1 Although the emollient was applied to the whole body the irritant reaction was confined to the external genitalia because the scrotal skin has remarkable permeability and hence is more susceptible to toxic and irritant agents. 6 It is important for clinicians to be aware of this adverse drug reaction when prescribing the treatment to a patient, because of the associated morbidity, especially in male patients, who could present with clinical features similar to Fournier's gangrene.…”

Section: Discussionmentioning

confidence: 99%

Acute irritant reaction to an antiseptic bath emollient

Saw

Hindmarsh

2005

Postgraduate Medical Journal

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Antiseptic bath emollients are commonly prescribed for treatment of eczema and are generally safe for frequent application. Although acute irritant reactions are uncommon it is nevertheless recognised and could have significant morbidity. This case describes a young male patient who developed an acute irritant reaction localised to the external genitalia, mimicking Fournier’s gangrene, after overnight application of Oilatum Plus antiseptic bath emollients.

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“…Especially patients with eczematous skin disorders are in need of nonirritating moisturizing skin care products. In addition to lipids, various other substances such as surfactants and fragrances are added to the bath oils that display cleansing and antiseptic effects and reduce itching [14][15][16] . However, recently an irritant potential of different bath and shower oils has been described [5] .…”

Section: Discussionmentioning

confidence: 99%

“…The consistent use of shower and bath oils leaves a protective lipid layer on the skin [11][12][13] . The use of bath oils displays positive effects such as cleansing, disinfection, reduction of pruritus and improvement of psychological well-being [14][15][16] .…”

mentioning

confidence: 99%

Skin Tolerance of a New Bath Oil Containing St. John’s Wort Extract

Reuter¹,

Huyke²,

Scheuvens³

et al. 2008

Skin Pharmacol Physiol

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Background: Dry and atopic skin requires skin care with lipid-rich emollients and moisturizing bath or shower oils. However, it has been shown recently that some bath oils may even impair the skin barrier. Objective: To investigate the skin-irritating potential of a new bath oil containing a lipophilic St. John’s wort (Hypericum perforatum) extract. Methods: In this single-center, randomized, double-blind, prospective study, 3 bath oils together with positive and negative controls were applied under occlusion on test areas on the volar forearms of 18 volunteers (visit 1). After 24 h, the tapes were removed, and the test areas were evaluated by a visual score and the instrumental measurement of skin erythema and transepidermal water loss (TEWL) using a Mexameter and a Tewameter (visit 2). The test substances were applied a second time, and the measurements were performed after another 24 h (visit 3). Results: The positive control, 1% vol/vol sodium lauryl sulfate (SLS), caused a significant increase in skin erythema and TEWL. In contrast, distilled water as a negative control did not influence these parameters. The new bath oil containing St. John’s wort extract and 1 of the other 2 commercial products were not different from the water control. The third bath oil displayed a skin-irritating effect similar to SLS. Conclusion: The results of this study confirm the different skin-irritating potential of bath oils and demonstrate good skin tolerance of the new bath oil containing St. John‘s wort extract.

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Irritant dermatitis due to prolonged contact with Oilatum PlusR

Cited by 24 publications

References 5 publications

Flexural allergic contact dermatitis to benzalkonium chloride in antiseptic bath oil

Flexural allergic contact dermatitis to benzalkonium chloride in antiseptic bath oil

Acute irritant reaction to an antiseptic bath emollient

Skin Tolerance of a New Bath Oil Containing St. John’s Wort Extract

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