“…Irritable bowel syndrome (IBS) is a frequent disorder of the lower gastrointestinal tract with characteristic abdominal pain or discomfort accompanied by altered bowel habits, including alterations in stool frequency and/or form or appearance, especially disordered defecation. [1][2][3][4][5][6][7] IBS can be sub-typed according to the predominant bowel movement type: IBS with constipation (C-IBS), IBS with diarrhea (D-IBS), and IBS with alternating symptoms of both constipation and diarrhea (A-IBS). 8,9 Despite intensive research, the complicated and multifactorial pathogenesis underlying IBS is not completely understood.…”