Irreversible enzymatic inhibition by cobalt chelate complexes

Böttcher, Arnd; Gray, Harry B.; Meade, Thomas J.; Simon, Melvin I.; Takeuchi, Toshihiko

doi:10.1016/0162-0134(95)97327-m

Cited by 31 publications

(29 citation statements)

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“…Co(III) Schiff bases have been extensively studied because of their interesting properties [1]. Many Co(III) pentacoordinate complexes have been synthesized and characterized [2,3].…”

Section: Introductionmentioning

confidence: 99%

Synthesis and characterization of tertiaryphosphinecobalt(III) Schiff base complexes and their thermodynamic study with organic bases in different solvents

Asadi

Ahmadi

Mohammadi

et al. 2004

The Journal of Chemical Thermodynamics

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“…Co(III) Schiff bases have been extensively studied because of their interesting properties [1]. Many Co(III) pentacoordinate complexes have been synthesized and characterized [2,3].…”

Section: Introductionmentioning

confidence: 99%

Synthesis and characterization of tertiaryphosphinecobalt(III) Schiff base complexes and their thermodynamic study with organic bases in different solvents

Asadi

Ahmadi

Mohammadi

et al. 2004

The Journal of Chemical Thermodynamics

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“…They play an important role in both synthetic and structural research [1][2][3]. In addition, recent investigations have shown that certain cobalt complexes are potent antiviral reagents [4], As an extension of our work on the structural characterization of Schiff base complexes [5][6][7], a new mononuclear Schiff base cobalt(II) complex is reported here. The Co(II) atom located on the inversion center is four-coordinated by two Ο and two imine Ν atoms from two Schiff base ligands, forming a tetrahedral environment.…”

Section: Discussionmentioning

confidence: 84%

Crystal structure of bis(4-bromo-2-((3-methylaminopropylimino)- methyl)phenolato)cobalt(II) dinitrate, [Co(C11H15BrN2O)2][NO3]2

Wang¹,

Pu²

2006

Zeitschrift Für Kristallographie - New Crystal Structures

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DiscussionCobalt complexes of Schiff bases have been extensively studied. They play an important role in both synthetic and structural research [1][2][3]. In addition, recent investigations have shown that certain cobalt complexes are potent antiviral reagents [4], As an extension of our work on the structural characterization of Schiff base complexes [5][6][7], a new mononuclear Schiff base cobalt(II) complex is reported here. The Co(II) atom located on the inversion center is four-coordinated by two Ο and two imine Ν atoms from two Schiff base ligands, forming a tetrahedral environment. The amine Ν atoms of the pendant propylaminomethyl units are protonated and do not take part in the coordination to the Co atom. The bond lengths and angles subtended at the Co center are typical and comparable to the values observed in other cobalt(II) complexes derived from Schiff bases [8][9][10]. The title compound crystallizes isostructurally with the analogous Zn compound [11]. Source of materialReagents and solvents used were of commercially available quality. 5-Bromo-2-hydroxybenzaldehyde (201.2 mg, 1.0 mmol), Nmethyl-l,3-diaminopropane (88.3 mg, 1.0 mmol) and Co(NÜ3)2 · 4H2O (127.5 mg, 0.5 mmol) were dissolved in ethanol (80 ml). The mixture was stirred for 20 min at room temperature to give a clear brown solution. Red block-shaped crystals, suitable for Xray structure determination were formed by slow evaporation of the solution in dark for a week. Elemental analysis -found: C, 36.20 %; H, 4.33 %; N, 11.72 %; calc. for C22H3oBr 2 CoN 6 08: C, 36.43 %; H, 4.17 %; Ν, 11.59 %.

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“…They play an important role in both synthetic and structural research [1][2][3]. Recent research show that certain cobalt complexes are potent antiviral reagents [4]. Herein we report the synthesis and crystal structure of a cobalt(II) complex derived from the Schiff base 4-bromo-2-(cyclopropyliminomethyl)phenol.…”

Section: Discussionmentioning

confidence: 99%

Crystal structure of bis(cyclopropyl-4-bromosalicylaldiminato)cobalt(II), Co(C20H18BrNO)2

Wei

Wang

2006

Zeitschrift Für Kristallographie - New Crystal Structures

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Source of materialReagents and solvents used were of commercially available quality. 5-Bromosalicylaldehyde (201.3 mg, 1.0 mmol), cyclopropylamine (57.2 mg, 1.0 mmol) and Co(CH 3 COO) 2 · 6H 2 O (142.6 mg, 0.5 mmol) were stirred and refluxed in ethanol at about 351 K for 30 min to give a red solution. Red block-shaped crystals, suitable for X-ray structural determination were formed by slow evaporation of the solution in dark for about a week. Elemental analysis found: C, 44.89 %; H, 3.45 %; N, 5.13 %; calc. for C20H18Br2CoN2O2: C, 44.72 %; H, 3.38 %; N, 5.22 %. Experimental detailsThe large ADP anisotropy for the C9 and C10 atoms is due to the disorder of the C8/C9/C10 cyclopropane ring. DiscussionCobalt complexes of Schiff bases have been extensively studied. They play an important role in both synthetic and structural research [1][2][3]. Recent research show that certain cobalt complexes are potent antiviral reagents [4]. Herein we report the synthesis and crystal structure of a cobalt(II) complex derived from the Schiff base 4-bromo-2-(cyclopropyliminomethyl)phenol. The Co II atom in the title complex is four-coordinated by two O and two N atoms from two Schiff base ligands, forming a tetrahedral coordination. All the bond lengths and angles subtended at the Co center are comparable to the corresponding values observed in other Schiff base cobalt complexes [5][6][7].

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Irreversible enzymatic inhibition by cobalt chelate complexes

Cited by 31 publications

References 0 publications

Synthesis and characterization of tertiaryphosphinecobalt(III) Schiff base complexes and their thermodynamic study with organic bases in different solvents

Synthesis and characterization of tertiaryphosphinecobalt(III) Schiff base complexes and their thermodynamic study with organic bases in different solvents

Crystal structure of bis(4-bromo-2-((3-methylaminopropylimino)- methyl)phenolato)cobalt(II) dinitrate, [Co(C11H15BrN2O)2][NO3]2

Crystal structure of bis(cyclopropyl-4-bromosalicylaldiminato)cobalt(II), Co(C20H18BrNO)2

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