Irradiation of regionally advanced carcinoma of the penis

Kragelj, Borut

doi:10.2478/v10019-009-0002-3

Cited by 2 publications

(5 citation statements)

References 9 publications

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“…In our case, metastases did not respond to palliative therapy and showed progression of the local disease. Despite the studies showed that rectal primaries had longer surviving comparing to genitor-urinary primary, we did not find any forms of result 7,8,10…”

Section: Discussioncontrasting

confidence: 88%

“…Peyronie’s disease, traumatic and infectious skin and syphilitic lesions or primary carcinoma of penis, must also be in the differential diagnosis of the penile metastasis. 2 , 7 …”

Section: Discussionmentioning

confidence: 99%

“…Treatment options are palliative with local surgery, systemic chemotherapy and local radiotherapy. 4 , 7 Surgery (panectomy) remains the only treatment with a long survival but mostly a patient dies in a year. Radiotherapy has an average survival of 8 months, whereas chemotherapy has not been studied for metastases from the rectum carcinoma.…”

Section: Discussionmentioning

confidence: 99%

“…Despite the studies showed that rectal primaries had longer surviving comparing to genitor-urinary primary, we did not find any forms of result. 7 , 8 , 10 …”

Section: Discussionmentioning

confidence: 99%

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A clinical case of the penile metastasis from the rectal carcinoma

Yıldırım

Coşkun²,

Purten³

et al. 2010

Radiology and Oncology

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BackgroundPenile metastases are rare and usually secondary to genitourinary and colorectal cancer.Case reportWe present a case of a 77-year-old man with penile metastasis who was operated for rectal carcinoma. He was referred to our clinic for penile ulcerous lesion, semierectile penis and voiding dysfunction. Imaging studies showed nodular lesion at glans penis and multiple bone metastases. He did not respond to chemoradiotherapy and he had bad prognosis.ConclusionsImaging methods and biopsy may help to clarify the diagnosis but the treatment modalities are insufficient in these patients.

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Section: Discussioncontrasting

confidence: 88%

“…Peyronie’s disease, traumatic and infectious skin and syphilitic lesions or primary carcinoma of penis, must also be in the differential diagnosis of the penile metastasis. 2 , 7 …”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…Despite the studies showed that rectal primaries had longer surviving comparing to genitor-urinary primary, we did not find any forms of result. 7 , 8 , 10 …”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

A clinical case of the penile metastasis from the rectal carcinoma

Yıldırım

Coşkun²,

Purten³

et al. 2010

Radiology and Oncology

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show abstract

“…There were only sporadic cases showed palliative operation, chemotherapy, or radiotherapy as management. Surgery with penectomy remains the optimal choice with the longest median survival time of 1 year; radiotherapy has an average survival of 8 months (3). We would like to review a case with secondary penile malignancy who underwent regional radiotherapy to the penis.…”

Section: Introductionmentioning

confidence: 99%

Radiotherapy to the rare penile metastases of rectal adenocarcinoma: a case report

Weng¹,

Yang²

2023

Ther Radiol Oncol

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Background: Malignant penile tumor is very rare, despite its nature is primary or secondary. Primary penile malignancy was reported with a very low incidence ranging from 0.58 to 1.3 cases per 100,000 people, and the incidence of secondary penile malignancy is much rarer, with no more than 500 cases reported yet.There are no standard treatment guidelines for secondary penile malignancy since its scarcity. Only sporadic cases showed palliative operation or radiotherapy as management. Surgery with penectomy remains the optimal choice with longest median survival time of 1 year; radiotherapy has an average survival of 8 months.Case Description: We reported a 69-year-old man with recurrent rectal adenocarcinoma, accompanied with lung, liver, and penile metastases. He suffered from penile tenderness, painful sensation, dysuria, and aggravated urine frequency due to his penile metastases, even under salvage chemotherapy and target therapy. Therefore, regional radiotherapy was applied to the penis, followed by apparent symptom relief.However, the time interval from the diagnosis of his penile metastases to his death was approximately 6 months, and the interval from the end of radiotherapy was 4 months. Among all the penile metastases reported before, one-third of the penile metastases were diagnosed in synchrony with the primary tumors, while the remaining two-thirds were noted within 18 months after the primary ones were diagnosed.Conclusions: When penile metastases were diagnosed, the majority of cases (90%) were found to have disseminated disease, with a survival time no longer than 12 months, which was associated with a very poor prognosis. For such patient, applying regional radiotherapy to the penis could play a palliative role for symptom relief, and might remain a better quality of life for the rest of the patient's life.

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Irradiation of regionally advanced carcinoma of the penis

Cited by 2 publications

References 9 publications

A clinical case of the penile metastasis from the rectal carcinoma

A clinical case of the penile metastasis from the rectal carcinoma

Radiotherapy to the rare penile metastases of rectal adenocarcinoma: a case report

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