A clinical case of the penile metastasis from the rectal carcinoma

Yıldırım, Mehmet; Coşkun, Ali; Purten, Mete; Öztekin, Özgür; İlhan, Enver

doi:10.2478/v10019-010-0004-1

Cited by 10 publications

(13 citation statements)

References 10 publications

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“…Patients with perianal skin invasion by rectal cancer present with symptoms of severe pain, continuous bleeding and distressing discharge, which significantly affect their quality of life. The indication for radical resection is controversial, as the survival benefits and surgical outcomes have not been clearly determined (9)(10)(11). In this study, we report a rare case after Anterior Rectal Resection with perineal skin involvement.…”

Section: Introductionmentioning

confidence: 85%

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A clinical case of perineal invasion from rectal carcinoma

Mitrushi¹

2017

GHIR

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Section: Introductionmentioning

confidence: 85%

“…Skin metastasis of cancer is rare, occurring in 0.7-5% of cancer patients (8)(9)(10)(11)(12). Breast cancer is the most common primary cancer with cutaneous metastasis, with an incidence of 24% according to a meta-analysis by Krathen et al (13).…”

Section: Discussionmentioning

confidence: 99%

A clinical case of perineal invasion from rectal carcinoma

Mitrushi¹

2017

GHIR

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“…Retrograde venous flow from the pudendal venous system onto the dorsal venous system of the penis, which provides routes for easy transportation of malignant cells, is considered the most likely mechanism. 2,6 Eberth reported the first case of secondary penile malignancy in 1870 and almost 400 cases were documented ever since.…”

Section: Discussionmentioning

confidence: 99%

“…Ultrasonography, CT, MRI and positron emission tomography are useful noninvasive methods for the metastatic disease evaluation and restaging. 6 The choice of treatment is greatly influenced by the performance status and primary cancer stage, but frequently has a palliative intention. Treatment options include penectomy, local surgical excision, radiation therapy, chemotherapy and supportive therapy.…”

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confidence: 99%

Metastasis to the Glans Penis: An Unusual Site of Rectal Cancer Recurrence

et al. 2015

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RESUMOA doença secundária do pénis é uma situação clínica frequentemente associada a doença disseminada e as localizações mais comuns são os órgãos genito-urinários. O prognóstico é mau e as opções de tratamento incluem: penectomia; excisão local; radioterapia; quimioterapia; terapêutica de suporte. Apesar das várias terapêuticas existentes, nenhuma na literatura é apontada como superior às restantes. Os autores documentam o caso de um doente de 66 anos com metástase da glande peniana em contexto de adenocarcinoma do recto, diagnosticada dois anos após o tratamento da doença primária. O doente foi submetido a tratamento paliativo com radio-quimioterapia e permanece assintomático e livre de doença após um ano de seguimento. O follow-up apertado dos doentes com neoplasia do recto é mandatório. A radio-quimioterapia é uma abordagem válida, com bom controlo da doença e melhoria sintomática. Palavras-chave: Metástases; Neoplasias do Pénis/secundária; Neoplasias do Recto; Radioterapia. ABSTRACTSecondary malignancy of the penis is a rare clinical condition, often associated with disseminated genitourinary malignancies. The prognosis is poor and the treatment options include penectomy, local surgical excision, radiation therapy, chemotherapy and supportive therapy. Neither of these therapeutic options lead to superior treatment outcomes in the literature. The authors report the case of a 66 year-old man with a metastasis to the glans penis from a rectal adenocarcinoma, diagnosed two years after radical treatment for primary disease. The patient underwent palliative treatment with radiotherapy and chemotherapy, remaining asymptomatic and disease-free at one year follow-up. Close follow-up of patients with history of rectal adenocarcinoma is very important. Radiochemotherapy is a feasible and effective therapeutic option for penile metastasis, addressing both disease control and symptomatic improvement.

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“…However, in general, for these patients, the indication for radical resection is controversial, as the survival benefits and surgical outcomes have not been clearly determined (6)(7)(8).…”

Section: Introductionmentioning

confidence: 99%

Successful treatment of rectal cancer with perineal invasion: Three case reports

Kitahara

Uemura

Haraguchi

et al. 2014

Molecular and Clinical Oncology

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Abstract. Rectal cancer occasionally invades adjacent organs. However, rectal cancer with perineal invasion is uncommon and difficult to treat. Locally advanced colorectal cancer may be clinically treated with neoadjuvant therapy, followed by en bloc resection. Skin invasion may lead to tumor dissemination via cutaneous blood flow and lymphatic routes. There is currently no firm evidence regarding the treatment of these significantly advanced rectal cancers. In this study, we report 3 cases of rectal cancer with perineal invasion, successfully managed by multimodality treatment. Case 1 is a 52-year-old man with rectal cancer that had invaded the perineum; case 2 is a 38-year-old man with rectal cancer infiltrating the perineal skin and liver metastasis; and case 3 is a 50-year-old woman with rectal cancer and perineal invasion. All the cases were treated with radical excision. No severe complications were observed in the perioperative period. Case 2, in particular, was confirmed to remain alive 5 years after the surgery. Our experience suggests that multimodality treatment, including extended radical surgery, may be a feasible approach to the treatment of rectal cancer with perineal skin invasion.

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A clinical case of the penile metastasis from the rectal carcinoma

Cited by 10 publications

References 10 publications

A clinical case of perineal invasion from rectal carcinoma

A clinical case of perineal invasion from rectal carcinoma

Metastasis to the Glans Penis: An Unusual Site of Rectal Cancer Recurrence

Successful treatment of rectal cancer with perineal invasion: Three case reports

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