Iron Stores in Pregnancy

Fenton, V.; Cavill, I.; Fisher, Jack B.

doi:10.1097/00006254-197807000-00002

Cited by 35 publications

(55 citation statements)

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“…Ferritin is not a useful measure as it falls dramatically in pregnancy irrespective of whether or not iron supplementation is given 22. Mean corpuscular volume usually remains fairly constant,22 however, and might prove to be a more robust indicator, although it can be confounded by the macrocytic effect of a simultaneous folate deficiency. Studies that link any variable proposed with fetal and neonatal function are needed lest we replace one misleading variable with another.…”

Section: Discussionmentioning

confidence: 99%

Relation between maternal haemoglobin concentration and birth weight in different ethnic groups

Steer

Alam²,

Wadsworth³

et al. 1995

BMJ

265

197

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Objective-To assess the relation of the lowest haemoglobin concentration in pregnancy with birth weight and the rates oflow birth weight and preterm delivery in different ethnic groups.Design Conclusions-The magnitude ofthe fall in haemoglobin concentration in pregnancy is related to birth weight; failure of the haemoglobin concentration to fall below 105 g/l indicates an increased risk of low birth weight and preterm delivery. This phenomenon is seen in all ethnic groups. Some ethnic groups have higher rates of low birth weight and preterm delivery than white women, and they also have higher rates of low haemoglobin concentrations. This increased rate of "anaemia," however, does not account for their higher rates of low birth weight, which occurs at all haemoglobin concentrations.

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Section: Discussionmentioning

confidence: 99%

Relation between maternal haemoglobin concentration and birth weight in different ethnic groups

Steer

Alam²,

Wadsworth³

et al. 1995

BMJ

265

197

View full text Add to dashboard Cite

show abstract

“…Fetal iron and folate utilization starts early in pregnancy leading to a rapid decline in iron stores and decreased serum ferritin. In addition, this process might be extremely stressful to the mother if maternal iron stores are low at the beginning of pregnancy [40]. Low serum ferritin before or during early pregnancy was reported to be a predictor of RLS occurring during the pregnancy [25].…”

Section: Methodsmentioning

confidence: 99%

Restless legs syndrome and pregnancy: A review

Srivanitchapoom

Pandey

Hallett

2014

Parkinsonism & Related Disorders

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Restless legs syndrome (RLS) is a common sensorimotor neurological disorder that is diagnosed according to the revised criteria of the International RLS Study Group (IRLSSG). The pathophysiology of RLS is still unknown and its prevalence is influenced by ethnicity, age, and gender. RLS is divided into two types by etiology: primary or idiopathic and secondary. Primary RLS is strongly influenced by a genetic component while secondary RLS is caused by other associated conditions such as end-stage renal disease or peripheral neuropathy. Another common condition associated with RLS is pregnancy. The prevalence of RLS during pregnancy is two to three times higher than in the normal population and is influenced by the trimester and the number of parity. The main mechanisms that may contribute to the pathophysiology of RLS during pregnancy are hormonal changes and iron and folate status. Standard medications for treating RLS during pregnancy are not established. Most medications have been used according to the evidence from non-pregnant patients. Therefore, consideration of the medical treatment for treating RLS during pregnancy should be balanced between the benefit of relieving the symptoms and maternal and fetal risk. In general, the prognosis of RLS during pregnancy is good and symptoms are usually relieved after delivery.

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“…Some authors suggest that the iron status (characterized by serum ferritin concentration) of pregnant women does not influence fetal iron stores (3)(4)(5)(6)(7)(8)(9)(10)(11)(12), others report that neonates born to females with subnormal serum ferritin levels show lower iron stores than neonates born to females with normal serum ferritin levels (13)(14)(15)(16)(17)(18)(19)(20)(21)(22).…”

mentioning

confidence: 99%

Does iron-deficient erythropoiesis in pregnancy influence fetal iron supply?

Harthoorn-Lasthuizen¹,

Lindemans²,

Langenhuijsen³

2001

Acta Obstet Gynecol Scand

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Background. It was investigated whether the iron status in newborns is negatively influenced by iron-deficient erythropoiesis of the mother during pregnancy. Methods. The iron status is characterized by hemoglobin, erythrocyte zinc protoporphyrin and serum ferritin values. Iron-deficient erythropoiesis of the mother is characterized by erythrocyte zinc protoporphyrin values. Measurement of erythrocyte zinc protoporphyrin was performed in 103 non-anemic females within 24 hours after delivery. The iron status of their newborns was measured in cord blood. Results. Erythrocyte zinc protoporphyrin concentrations were normal in 62% and elevated in 38% of the females, hence 39 women had iron-deficient erythropoiesis. There were no significant differences in mean values of the iron status parameters between neonates born to females with iron-deficient erythropoiesis and neonates born to females not having iron-deficient erythropoiesis. No correlation was found between maternal erythrocyte zinc protoporphyrin values and any of the neonatal parameters. Conclusion. It is concluded that fetal iron supply is not negatively influenced by iron-deficient erythropoiesis in the mother.

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Iron Stores in Pregnancy

Cited by 35 publications

References 0 publications

Relation between maternal haemoglobin concentration and birth weight in different ethnic groups

Relation between maternal haemoglobin concentration and birth weight in different ethnic groups

Restless legs syndrome and pregnancy: A review

Does iron-deficient erythropoiesis in pregnancy influence fetal iron supply?

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