Iron status in obese women

“…9 Stankowiak-Kulpa H et al, showed that obese women were characterized by a significantly lowere mean Red blood cell volume, serum iron level, and transferrin saturation. 10 Study conducted by Zhao L et al, concluded that obesity is significantly associated with iron deficiency, and early monitoring and treatment of iron deficiency and obese individuals was recommended. 11 Study conducted by Chambers EC et al, showed an inverse association of measures of body fat distribution and total fat mass with serum iron level in Hispanic women.…”

Section: Iron and Tibcmentioning

confidence: 99%

Comparative evaluation of iron profile in premenopausal obese women with women of normal body mass index

et al. 2020

View full text Add to dashboard Cite

Background: Obesity has become a common problem worldwide due to changes in lifestyle and food habits. Obesity has been associated with many chronic diseases like diabetes mellitus, hypertension, gallstones etc. Excessive adipose tissue through release of adipokines maybe a risk factor for derangements in iron parameters. Authors aim is to study Serum Iron, TIBC, and Serum Ferritin levels in Obese women (BMI >25 kg/m2) in age group of 16 to 45 years and its comparison with normal BMI women.Methods: The case control study was conducted on 100 patients divided into two groups. Group A included 50 patients of obese women (BMI >25 kg/m2) in age group of 16 to 45 years. Group B consists of 50 control patients in similar age group with BMI of 18-23 kg/m2. Serum Iron, TIBC, and Serum Ferritin levels were measured in both groups and compared.Results: The study showed significant derangements of iron parameters in obese women.Serum Ferritin was significantly raised (p<0.001) in obese women whereas Serum Iron and TIBC were significantly decreased in obese women as compared to control group. No significant difference was seen in Serum Hemoglobin and MCV.Conclusions: Obesity is associated with derangements in iron parameters in women of reproductive age group similar to derangements seen in chronic inflammatory state.

show abstract

“…Scientific reports have shown that iron deficiency is positively associated with adiposity [7]. In this sense, a decreased concentration of iron, and consecutively haemoglobin, ferritin and decreased level of saturated transferrin, were observed in obese individuals more often than in normal weight subjects [8]. Loss of appetite, retarded growth and development are typical manifestations of the nutritional ferropenic anemia; however, hormonal control for body composition changes during IDA has been not yet fully explained.…”

Section: Introductionmentioning

confidence: 99%

Iron Deficiency and Neuroendocrine Regulators of Basal Metabolism, Body Composition and Energy Expenditure in Rats

et al. 2019

View full text Add to dashboard Cite

Although dietary iron is a determinant of iron status in animals, body fat mass has been reported to have an inverse association with iron status in human studies. The goal of this study was to determine the relationship between Fe homeostasis, body composition, energy expenditure and neuroendocrine regulators for severe Fe-deficiency anaemia. Forty male Wistar albino rats recently weaned were divided at random into two groups: the control group was fed the basal diet, AIN-93G diet (normal-Fe) and the anaemic group received a low-Fe diet for 40 days. Neuroendocrine parameters that regulate basal metabolism and appetite (thyroid hormones, ghrelin, glucose-dependent insulinotropic polypeptide (GIP), glucagon, insulin, adrenocorticotropic hormone and corticosterone), body composition, respiratory volumes, energy expenditure, haematological and biochemical were assessed. Total body fat was lower, whereas lean mass, free and total water were higher in the anemic group. O2 consumption, CO2 production, energy expenditure (EE) and respiratory quotient (RQ) were lower in the Fe-deficient animals. Triiodothyronine and thyroxine hormones decreased, while thyroid-stimulating hormone increased in the anemic group. Circulating levels of ghrelin were lower in the anemic group, while GIP, glucagon, insulin, corticosterone and adrenocorticotropic hormone levels were higher. Fe-deficiency impairs weight gain in the rats, with marked reductions in lean mass and body fat, indicating lower energy stores.

show abstract

Iron status in obese women

Cited by 13 publications

References 24 publications

Obesity and iron-deficiency anemia in women of reproductive age in northern Iran

Obesity and iron-deficiency anemia in women of reproductive age in northern Iran

Comparative evaluation of iron profile in premenopausal obese women with women of normal body mass index

Iron Deficiency and Neuroendocrine Regulators of Basal Metabolism, Body Composition and Energy Expenditure in Rats

Contact Info

Product

Resources

About