Iron Oxide and Gold Based Magneto-Plasmonic Nanostructures for Medical Applications: A Review

Abstract

Iron oxide and gold-based magneto-plasmonic nanostructures exhibit remarkable optical and superparamagnetic properties originating from their two different components. As a consequence, they have improved and broadened the application potential of nanomaterials in medicine. They can be used as multifunctional nanoprobes for magneto-plasmonic heating as well as for magnetic and optical imaging. They can also be used for magnetically assisted optical biosensing, to detect extreme traces of targeted bioanalytes. This review introduces the previous work on magneto-plasmonic hetero-nanostructures including: (i) their synthesis from simple “one-step” to complex “multi-step” routes, including seed-mediated and non-seed-mediated methods; and (ii) the characterization of their multifunctional features, with a special emphasis on the relationships between their synthesis conditions, their structures and their properties. It also focuses on the most important progress made with regard to their use in nanomedicine, keeping in mind the same aim, the correlation between their morphology—namely spherical and non-spherical, core-satellite and core-shell, and the desired applications.

Multifunctional Fe3O4-Au Nanoparticles for the MRI Diagnosis and Potential Treatment of Liver Cancer

“…On the other hand, gold NPs of different sizes and shapes have been investigated as photo-thermal/photo-acoustic agents for tumor diagnosis and therapy [25,26], computed tomography (CT) contrast agents [27,28], biosensors [29,30] and catalysts [31,32]. Combining the optical and magnetic properties of gold and magnetite in hybrid nanostructures can thus enhance their functionality and pave the way towards multimodal applications [33]. As an example, the strong contrast in MRI and X-ray CT suggests that the magneto-plasmonic NPs have a large potential as efficient multi-modal imaging probes [34].…”

Optical and Magnetic Properties of Ag–Ni Bimetallic Nanoparticles Assembled via Pulsed Laser-Induced Dewetting

“…Chemical growth techniques 1 are most commonly utilized for fabricating magneto-plasmonic nanoparticles; however, another highly robust technique exists: pulsed laser-induced dewetting (PLiD). 8 − 11 PLiD exploits the inherent metastability of a metallic thin film on a substrate.…”

Synthesis and Properties of Magnetic Self‐Healing Polymers: An Effective Method for Improving Interface Compatibility of Doped Functional Polymers

“…Magnetic nano materials, have been regarded as newly‐developing materials due to its superior properties and has been widely applied in many fields such as mechanical electronics, military, biology, medical science, et al . In all magnetic nano materials, Fe 3 O 4 nanospheres (NPs) are thought to be the best for its advantages in stability, magnetic properties, biocompatibility, easy fabrication and low cost.…”

“…Magnetic nano materials [14,15] have been regarded as newlydeveloping materials due to its superior properties and has been widely applied in many fields such as mechanical electronics, military, biology, medical science, et al [16][17][18][19][20][21][22] In all magnetic nano materials, Fe 3 O 4 nanospheres (NPs) are thought to be the best for its advantages in stability, magnetic properties, biocompatibility, easy fabrication and low cost. Recently, many researchers have applied Fe 3 O 4 NPs into self-healing polymers such as elastomers, sensors, actuators, rubbers and instance synthetic polymers to fabrication magnetic self-healing polymers, [23][24][25][26][27][28][29][30] which can also be repaired when added an external magnetic field after it is damaged.…”