Iris cyst simulating melanoma

Don’t it make my blue eyes brown: heterochromia and other abnormalities of the iris

“…156,176,177 Focal corneal oedema may arise as a result of contact between the stromal cyst and the corneal endothelium. 137,142,161,163 Raised intraocular pressure, 159,163,172,173 hyphaema 137 iritis, and subluxation of the lens 163,167,171,[173][174][175] have been found in association with primary iris stromal cysts.…”

“…163 Histologically, primary iris stromal cysts are lined with a multi-layered squamous or cuboidal epithelium, which may or may not contain mucin-secreting goblet cells. 138,139,142,163,[168][169][170]173,174,178,179 Occasionally, focal keratinisation of the epithelial lining has been observed. 170,180 Immunohistochemical studies have demonstrated a positive reaction for epithelial cytokeratin markers and a negative result for the S100 antigen.…”

“…A wide range of modalities have been used to treat symptomatic primary iris stromal cysts, including simple aspiration, 155,171 and injection with trichloroacetic acid, 158 xenon photocoagulation, 158 neodymium-YAG laser, 164,171 argon laser photocoagulation, 155,181 cryotherapy, 155,181 iridectomy, 158,142 and block excision. 160,180 Unfortunately, re-occurrence following treatment, particularly simple puncture either surgical or laser, is common and prognosis for vision, particularly in young children where amblyopia may be a problem, is often poor.…”

Quiste de iris. A propósito de un caso.

“…Los primarios de la zona medial por su gran tamaño, coloración oscura, y la ausencia de transiluminación debe ser diferenciada de entidades como el melanoma de iris o del cuerpo ciliar. Los quistes de implantación secundaria y crecimiento epitelial deben diferenciarse de la proliferación endotelial secundaria, síndrome endotelial iridocorneal y carcinomas metastásicos 8 .…”

Ab externo laser photocoagulation for the treatment of spontaneous iris stromal cyst

“…Occurring most commonly in children, it presents as a round, translucent mass, readily seen in the anterior chamber and often arising from the inferior part of the iris [1][2][3]. Occasionally it can be pigmented and misdiagnosed as melanoma [4]. Most patients require surgical intervention due to its progressive growth obstructing the visual axis resulting in poor vision from amblyopia or secondary glaucoma.…”