Ionic Liquids for Development of Heterogeneous Catalysts Based on Nanomaterials for Biocatalysis

Abstract

The development of effective methods of enzyme stabilization is key for the evolution of biocatalytic processes. An interesting approach combines the stabilization process of proteins in ionic liquids and the immobilization of the active phase on the solid support. As a result, stable, active and heterogeneous biocatalysts are obtained. There are several benefits associated with heterogeneous processes, as easy separation of the biocatalyst from the reaction mixture and the possibility of recycling. Accordingly, this work focused on the supported ionic liquid phases as the efficient enzyme stabilization carriers, and their application in both continuous flow and batch biocatalytic processes.

Research progress and applications of silica-based aerogels – a bibliometric analysis

“…[202][203][204] Compared with catalysts alone, catalysts loaded on SAs not only improved stability but also are easier to facile recovery and reuse. 205,206 For example, Lisboa et al 207 loaded lipase onto SAs. Aer incubation at 40 C for 6 days, free lipase was inactivated, while the activity of lipase loaded on SAs was more than 50%.…”

Novel Glucosylimidazolium Ionic‐Liquid‐Supported Novozym 435 Catalysts – A Proof of Concept for an Acrylation Reaction

“…[12] As part of our continued interest in optimizing the syntheses and applications of carbohydrate-based ionic liquids (CHILs), [13][14][15] a rapidly growing topic in the recent years, [16] we were investigating the use of CHILs in biocatalysis. Ionic liquids are generally well-known in biocatalysis, for example as reaction medium [17] or as support for the immobilized enzymes, [18] amongst other uses. Recent work from Boncel, Chrobok et al…”

Ionic Liquid Modification Optimizes the Interface between Lipase and Magnetic GO for Enhancing Biocatalysis

“…25 To completely utilize the enhanced properties of ILs and reduce their use, ILs as modifiers or bridging molecules for enzyme immobilization is a feasible way. 25 As reported that imidazole-based ILs were covalently grafted onto magnetic composites and the synthesized composites were used as supports for lipase immobilization. The immobilized lipase was used for the production of trans-free plastic and showed good catalytic activity and magnetic response.…”