Ion-selective optical sensor for continuous on-line monitoring of dialysate sodium during dialysis

Sharma, Manoj K.; Frijns, Ajh Arjan; Mandamparambil, Rajesh; Kooman, Jeroen P.; Smeulders, David

doi:10.1117/12.2251923

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Other Technical Reasons For Dialysate Sodium Variations1

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2018

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“…The ISE technology would certainly be more precise than evaluation merely via conductivity [28,29,30,23], but it is a too "fragile" technology. Far better would be the spectrophotometric approach [31], but it is still in the experimental stage.…”

Section: Other Technical Reasons For Dialysate Sodium Variationsmentioning

confidence: 99%

Fallacies and Pitfalls of Dialysis Sodium Prescription and Control

et al. 2018

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Dialysate conductivity is routinely used as a surrogate for dialysate sodium concentration. However, dialysis machine manufacturers apply different conductivity temperature correction coefficients. With the same conductivity in dialysis machines manufactured by different manufacturers, dialysate sodium may significantly differ. Also, electrolyte prescriptions are individualized (K, Ca, HCO³) and this is associated with another variation in dialysate sodium in the order of 1–5 mmol/L and both deviations are cumulative and chronic for each patient. Equivalence of the prescribed dialysate sodium and the concentration measured in it is not granted. Both variables differ and it is machine dependent! This paper analyses those variations from a technical point of view and suggests how to detect them and how to deal with or avoid them in clinical practice.

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