Ion Association and Solvation of Sulfathiazole Sodium in Aqueous and Partial Aqueous Media

Abstract

The electrical conductance of sulfathiazole sodium in water and different volume fractions of water + dimethyl sulfoxide (DMSO) and water + ethanol in the temperature range of (283 to 313) K has been measured. Kraus-Bray and Shedlovsky models of conductivity were used for analyzing the conductance data. The limiting ionic conductance, limiting molar conductance, and association constant, K a , have been determined. On the basis of the viscosity of the solvent, the Walden product and Stokes molecular radius were also determined.

The effect of temperature on association constants and conductivities of ferrous chloride and ferric chloride in DMF-water mixtures

“…The hydrogen bond formed between DMF and water is stronger than in pure water due to dipole-dipole interaction, which leads to the association of DMF and water molecules, leading to the reduction in ionic mobility [28].…”

“…The variation in KA to another from one composition in 20-80 wt % DMF-water mixtures is primarily due to the change in relative permittivity and also due to the formation of intermolecular hydrogen bonding, causing not only an increase in the thickness of the ionic atmosphere surrounding the polar species but also a reduction in the repulsion between them. The decrease in the hydration of the ions, due to the presence of solvent mixture molecules, leads to an increase in the association constant values [10,11,28].…”