Iodide Mumps After Repeated Exposure to Iodinated Contrast Media

Cohen, J.B.; Roxe, DavidM.; Said, Riyad; Cummins, George

doi:10.1016/s0140-6736(80)91251-9

Cited by 20 publications

(4 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It has been suggested that the high serum iodide levels observed in uremic patients as a consequence of delayed renal iodide excretion and prolonged iodide off-splitting from the contrast molecules (24,25) dispose to toxic accumulation of iodide in the salivary ductal systems; this in turn should lead to ductal cell swelling and at least partial obstruction of the ducts with consequent inflammatory swelling of salivary glands. This theory is supported by the observations of CoHEN et al (4) and REUTER & EUGSTER (21) who noted an apparent relation between high serum levels of inorganic iodide and onset and extent of iodide mumps in uremic patients.…”

Section: Discussionsupporting

confidence: 60%

Iodide Mumps after Intravascular Administration of a Nonionic Contrast Medium

Christensen¹

1995

Acta Radiol

View full text Add to dashboard Cite

Swelling of the submandibular, sublingual and/ or parotid glands ("iodide mumps") is an uncommon complication to intravascular administration of contrast material. The etiology remains unclear, but the reaction seems to be idiosyncratic or related to toxic accumulation of iodide in the ductal systems of the salivary glands. The introduction of nonionic contrast media has not eliminated the risk of developing iodide mumps. The first reported case of iodide mumps after intravascular administration of iopromide (Ultravist 300) is presented.

show abstract

Section: Discussionsupporting

confidence: 60%

Iodide Mumps after Intravascular Administration of a Nonionic Contrast Medium

Christensen¹

1995

Acta Radiol

View full text Add to dashboard Cite

show abstract

“…We identified only 36 cases of iodide sialadenitis 2 – 32 (22 men, 14 women; mean age, 60.0 ± 13.6 years; age range, 8–78 years). Of these 36 patients, 19 had received intravenous injections, 2 , 6 – 13 , 16 , 18 , 24 , 25 , 28 , 32 10 had undergone arteriography 3 , 4 , 17 , 19 , 20 , 22 , 23 , 26 , 27 , 29 (1 case occurred after carotid artery stenting 4 ), 4 had ingested an iodine compound, 5 , 14 , 30 2 had undergone both arteriography injections and ventriculography, 21 and 1 was exposed to oral and intravenous iodide contrast media. 31 We found that iodide mumps can occur after intravenous, intra-arterial, oral, or ventricular iodide administration.…”

Section: Discussionmentioning

confidence: 99%

Acute Submandibular Swelling Complicating Arteriography With Iodide Contrast

Zhang

et al. 2015

Medicine

View full text Add to dashboard Cite

Iodide mumps is an uncommon condition induced by iodide-containing contrast. We present the first reported case of iodide mumps in mainland China, which occurred after carotid artery intervention.The patient, a 65-year-old Chinese male, had a history of dizziness, hypertension, diabetes, and right arm weakness. He had no history of allergies and had never previously received iodide-containing contrast. The patient's kidney function and other laboratory findings were normal. He underwent stenting of the left internal carotid artery (LICA) opening and received approximately 250 mL of a nonionic contrast agent (ioversol). Approximately 5 hours after angioplasty, bilateral local swellings were noted near the mandible; the masses were moderately firm and nontender.Iodide mumps was diagnosed in the patient. Intravenous dexamethasone (10 mg) was administered. The submandibular glands had shrunk by 11 hours after angioplasty, and they gradually became softer. The mandibular salivary glands had completely recovered by 5 days after surgery.Iodide mumps represents a rare late reaction to iodine-containing contrast media. This condition can occur in any patient receiving any iodinated contrast agent and may recur upon repeated exposure, but self-resolution can be expected within 2 weeks. All clinicians who use contrast media or iodide should be aware of this condition.

show abstract

“…This trapping causes ductal cell swelling and partial obstruction of the ducts with an inflammatory response of the salivary gland expressed as sialadenitis [4]. This theory is supported by an observation done by Cohen et al [5], which showed an association between high serum levels of iodine in uremic patients, and the extent and onset of iodine induced mumps. Another supporting fact is that in patients undergoing hemodialysis, dialysis after exposure to contrast material has been shown to shorten the duration of symptoms [4].…”

Section: Discussionmentioning

confidence: 89%

Recurrent iodine contrast induced sialadenitis: Case report

Potruch¹,

Azmanov²

2021

J Clin Images Med Case Rep

View full text Add to dashboard Cite

Iodine induced sialadenitis is an uncommon condition, induced by exposure to iodine-containing contrast material. Although the condition had been reported in the past, the incidence and pathogenesis of this condition is not well understood, and is thought to be caused by either toxic damage from accumulation of iodine in the salivary glands and ducts, or from renal damage leading to iodine excretion disorder. We present a case of a patient with three separate events of parotid enlargement in reaction to iodine contrast material exposure.

show abstract

Iodide Mumps After Repeated Exposure to Iodinated Contrast Media

Cited by 20 publications

References 4 publications

Iodide Mumps after Intravascular Administration of a Nonionic Contrast Medium

Iodide Mumps after Intravascular Administration of a Nonionic Contrast Medium

Acute Submandibular Swelling Complicating Arteriography With Iodide Contrast

Recurrent iodine contrast induced sialadenitis: Case report

Contact Info

Product

Resources

About