Abstract:IntroductionIn rodents, the parafacial respiratory group (pFRG), located in the ventral lateral medulla, has been described as a conditional expiratory oscillator that emerges mainly in conditions of metabolic challenges to increase ventilation. However the mechanisms required to stimulate pFRG and generate active expiration have not been fully elucidated. Because the raphe region has long been described to be involved in breathing activity, we decided to investigate whether there were projections from raphe t… Show more
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