InVitro Antioxidant and Free Radical Scavenging Activity of Withania Somnifera Root

Shahriar, Mohammad

doi:10.9790/3013-32203847

Cited by 28 publications

(24 citation statements)

References 23 publications

(19 reference statements)

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“…As the concentration increases the free radical scavenging activity of plant extract also increases. The data depicts that IC50value was 54µg/ml for W. somnifera and 69µg/ml for W. coagulans which was lower value according to data shown by Shariar 18 IC-50= 54µg/ml IC-50= 69µg/ml Alam 19 that the Withania somnifera extracts was 101.73-801.93 μg/ml at IC50 which indicated higher value from present data.…”

Section: Fig1: Scavenging Effects Of the Aqueous Extract Of Withaniamentioning

confidence: 58%

In Vitro Study on total Phenols, Flavonoids Content and DPPH Activity of Withania Species

Raj¹,

Agarwal²,

Chaturvedi³

2017

IJEAB

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Section: Fig1: Scavenging Effects Of the Aqueous Extract Of Withaniamentioning

confidence: 58%

In Vitro Study on total Phenols, Flavonoids Content and DPPH Activity of Withania Species

Raj¹,

Agarwal²,

Chaturvedi³

2017

IJEAB

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“…The study of Vuong et al [24] reported that TPC of papaya leaf extracted by various solvents was decreased in order of water, methanol, acetone and ethanol (23.06, 15.03, 10.71 and 9.43 mg GAE/g dry weight, respectively). Previous study of Shahriar et al [29] found that TPC of W. somnifera root was decreased in order by chloroform, petroleum ether, methanol, ethanol and n-hexane (60.99, 56.58, 23.86, 5.46 and 1.43 mg GAE/g dry weight, respectively). To compare with other plants, TPC of carrot peel was much higher than that of Sage plants [30] (approximately 2.3 mg GAE/g dry weight), but it was lower than those of Oolong tea [22] and papaya leaf [24] (13.58 and 15.03 mg GAE/g dry weight, respectively), and being much lower than those of P. amarus/urinaria/niruri [27] (50.24, 62.56 and 68.70 mg GAE/g dry weight, respectively).…”

Section: Total Phenolic Contentmentioning

confidence: 99%

“…In comparison between the extracts of W. somnifera root using different solvents with ascorbic acid and BHT, the study of Shahriar et al [29] indicated that the extracts obtained by chloroform, petroleum ether and methanol possessed the greatest DRSC. In contrast, the extracts gained by ethanol and n-hexane had the lowest DRSC.…”

Section: Dpph Radical Scavenging Capacitymentioning

confidence: 99%

Mass Proportion, Bioactive Compounds and Antioxidant Capacity of Carrot Peel as Affected by Various Solvents

Nguyen

Scarlett

2016

Technologies

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Abstract:The aim of this study was to determine the mass proportion of carrot root and the effects of four various solvents (methanol, water, ethanol and hexane) on the contents of total phenolics and saponins as well as antioxidant capacity of carrot peel to identify an optimal solvent for effective extraction of bioactive compounds from carrot peel for further investigation. The results showed that carrot root consisted of body, heads and peel with their mass proportion of 83.19%, 5.01% and 14.19% by fresh weight, respectively. Among four solvents tested, methanol obtained the highest levels of extraction yield (54.02% by dry weight), total phenolic content (9.02 mg GAE/g dry weight) and antioxidant capacity (DPPH radical scavenging capacity, cupric ion reducing antioxidant capacity, and ferric reducing antioxidant power) from carrot peel, while water extracted the highest content of saponins (272.9 mg EE/g dry weight) and possessed the maximum ABTS radical scavenging capacity. Therefore, methanol and water are considered for effective extraction of phenolics and saponins from carrot peel, respectively. The phenolic/saponin-enriched extracts are potential sources for further applications in the healthy food and/or pharmaceutical industries.

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“…Total antioxidant capacity (TAC) [13], reducing power [14], and hydrogen peroxide scavenging activity [15] of M. tinctoria aqueous extract were assessed as prescribed earlier. The free radical scavenging assays such as 1, 1-diphenyl 2-picrylhyorazyl (DPPH) and 2, 2-Azinobis-(3 ethylbenzothiazoline-6-sulfonic acids) (ABTS) were performed to determine the free radical scavenging property of M. tinctoria extract as detailed in the previous studies [15][16][17].…”

Section: Assessment Of Antioxidant Activitiesmentioning

confidence: 99%

Evaluation of Bioactivities of Morinda Tinctoria Leaves Extract for Pharmacological Applications.

Sivakumar¹,

Sivamaruthi

Priya³

et al. 2018

Asian J Pharm Clin Res

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Objective: The present study was aimed to prepare Morinda tinctoria leaves extracts with the different solvent system and to evaluate the bioactivities. Methods:The extracts of M. tinctoria were qualitatively analyzed for the primary phytochemical content. The functional groups of extract were determined by Fourier-transform infrared spectroscopy (FT-IR) analysis. The antimicrobial properties were determined by plate assays. The antioxidant and in vitro antiinflammatory properties and membrane stabilizing nature of aqueous extract of M. tinctoria (AEM) were measured using a spectrophotometer. Results:The aqueous, ethanolic, and acetone extracts of M. tinctoria were prepared. AEM contains quinones, steroids, terpenoids, phenols, glycosides, and tannins. FTIR result showed that AEM comprises of alkyl halides, 1°, 2° amines, aromatics, aliphatic amines, alcohols, carboxylic acids, esters, ethers, and alkanes, saturated aliphatic, and phenolic groups. The antimicrobial property of M. tinctoria varied based on the solvent used for the extraction. About 86.90±0.36, 78.58±0.13, and 80.33±0.09% of total antioxidant capacity, reducing power, and hydrogen peroxide scavenging activity were observed in AEM, respectively. The 1, 1-diphenyl 2-picrylhyorazyl and 2, 2-Azinobis-(3 ethylbenzothiazoline-6-sulfonic acids) assay results indicated 85.20±0.50 and 52.41±0.60% of free radical scavenging activity in AEM. The protease activity (44.10±0.26%) and protein degradation (44.38±0.58%) were proscribed by AEM. AEM prevents 69.36±0.20% of cell lysis. Conclusion:The results revealed that the AEM leaves were harmless and enriched with potent bioactive principles, which is further used for food and pharmacological applications.

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InVitro Antioxidant and Free Radical Scavenging Activity of Withania Somnifera Root

Cited by 28 publications

References 23 publications

In Vitro Study on total Phenols, Flavonoids Content and DPPH Activity of Withania Species

In Vitro Study on total Phenols, Flavonoids Content and DPPH Activity of Withania Species

Mass Proportion, Bioactive Compounds and Antioxidant Capacity of Carrot Peel as Affected by Various Solvents

Evaluation of Bioactivities of Morinda Tinctoria Leaves Extract for Pharmacological Applications.

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