“…Adrenaline, dopamine, and methyl dopa (35) were estimated using this reaction. The oxidative coupling reactions are crucial in the determination of a variety of pharmacological compounds, especially organic compounds, as well as many metal ions as applied spectral methods (36,37,38), chromatography (39), and flow injection analysis (40) are used to analyze many important compounds in agriculture, food, and the environment, as well as clinical and pharmaceutical analyses. The nature of the reacted materials, the reaction conditions, and the stability of the colored products in the various reactions all have an effect on the reactions of oxidative coupling, with the probability of obtaining it in acidic, alkaline, or neutral medium depending on the nature of the reacted materials, the reaction conditions, and the stability of the colored products in the various reactions (41).…”