Investigation on Mechanical and Bio-Mechanical Performance of a Centrifugal Blood Pump

Centrifugal blood pumps have to be considered from both mechanical and biomechanical aspects. While, evaluations of mechanical factors, such as performance curve, are straightforward, biomechanical parameters, such as hemolysis indices, are still indistinct. Hence, different mathematical models and computational methods have been employed for the evaluation of hemolysis indices. This article aims to investigate four different types of centrifugal blood pumps from both mechanical and biomechanical aspects. The pumps are conetype impeller (Type-A), channel-type impeller with shroud (Type-B), open impeller without shroud (Type-C) and shrouded impeller-type (Type-D). The CFD simulations are conducted using standard k-ε turbulence model in multiple reference frame (MRF) method. Various values for rotational speed and flow rate are studied. The streamlines clearly show the effects of impeller geometry on flow patterns. It is also demonstrated that in all of the models, the areas of the recirculation have high value of von Mises stress. In addition, the effect of the volute in the Type-D on the pressure distribution and streamline smoothness is clearly observed. In another part, the modified index of hemolysis (MIH) calculated based on Eulerian approach is investigated for three predefined conditions of extracorporeal membrane oxygenation (ECMO), ventricular assist device (VAD), and full-load. The results reveal that the Type-A and Type-D have the highest and lowest MIH values, respectively in all of the predefined conditions. In addition, all of the pumps generate lower amount of hemolysis when they are operated in VAD condition.

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“…As Chang et al [22] presented, the results of this MIH method are in good agreement with the experimantal results of De Wachter et al [23].…”

Section: Mih Calculationsupporting

confidence: 85%

A Numerical Study on Mechanical Performance and Hemolysis for Different Types of Centrifugal Blood Pumps

Chang

Hur

Moshfeghi

et al. 2015

Volume 3: Biomedical and Biotechnology Engineering

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“…According to comparison presented by Chang et al [16], the MIH values calculated based on this method in agreement with experiment.…”

Section: Mih Calculationsupporting

confidence: 70%

“…The geometry pumps is determined based on work done by Chang et al [16] and their investigation on the existing commercial blood pumps. Later, two more modified models are also designed and simulated.…”

Section: Geometry Of Pumpsmentioning

confidence: 99%

Development of a Centrifugal Blood Pump for Ecmo and Vad Operations

Choi¹,

Hur²,

Moshfeghi³

et al. 2016

Proceedings of the VII European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS Congress 2016)

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Using cardiopulmonary circulatory assist devices has been increased in the recent years as more models are available in the market. These devices can be employed in the situation during which both cardiac and respiratory support to a patient's heart and lungs have to be provided, either during or after surgeries, for short time or even in the case of severe disease, for a period of weeks. Hence, it is critical to know the details of the phenomena happen inside a blood pump from both mechanical performances (such as pressure head and mechanical efficiency) and biomedical factors (such as hemolysis and thrombosis) and to design an optimum pump from both aspects. This paper investigates development of centrifugal blood pump impeller, specifically with focusing on the performances during ECMO condition. The baseline model is designed by investigating existing commercial pumps and considering results of recirculation, pressure heads and mechanical efficiencies together with their biomechanical performance via Modified Indices of Hemolysis (MIH). Afterword, two more modified models are designed and simulated. Overall, a comprehensive comparison between the results of all three case demonstrate that when impeller radius and prime volume is smaller, recirculation is reduced at impeller and MIH value becomes lower. Additionally, high scalar shear stress is observed near the volute and impeller walls and inside the top cavity gap.

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Evaluation of Lagrangian and Eulerian Approaches for Prediction of Hemolysis in Blood Pumps

Hong¹,

Son²,

Hur³

et al. 2015

Journal of computational fluids engineering

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Investigation on Mechanical and Bio-Mechanical Performance of a Centrifugal Blood Pump

Cited by 4 publications

References 17 publications

A Numerical Study on Mechanical Performance and Hemolysis for Different Types of Centrifugal Blood Pumps

A Numerical Study on Mechanical Performance and Hemolysis for Different Types of Centrifugal Blood Pumps

Development of a Centrifugal Blood Pump for Ecmo and Vad Operations

Evaluation of Lagrangian and Eulerian Approaches for Prediction of Hemolysis in Blood Pumps

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