Investigation of the optimal weight contents of reduced graphene oxide–gold nanoparticles composites and theirs application in electrochemical biosensors

Bai, Xiaoyun; Shiu, Kwok Keung

doi:10.1016/j.jelechem.2014.03.031

Cited by 18 publications

(9 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The use of graphene/NP composite materials in glucose biosensors has been further demonstrated by Bai and Shiu, who showed that a rGO/AuNP-modified GCE can be further modified to detect glucose when a layer of chitosan/GOx is coated onto the rGO/Au surface. 139 The fabricated sensor exhibits an impressive LOD of 76 μM, with a retention of sensitivity for 0.1 mM of glucose after 36 days of >70% of the original sensitivity.…”

Section: Overview Of Carbon-based Voltammetric Biosensorsmentioning

confidence: 94%

“…The authors showed that this biosensor has a LOD of 0.05 mM, a linear sensing range of 0.5–12 mM, and a response time of ∼6 s. Importantly, the authors demonstrated that the rGO/Fe 3 O 4 -modified GCE readily immobilizes biomolecules, such as human immunoglobulin E, making this a readily applicable biosensing material. The use of graphene/NP composite materials in glucose biosensors has been further demonstrated by Bai and Shiu, who showed that a rGO/AuNP-modified GCE can be further modified to detect glucose when a layer of chitosan/GOx is coated onto the rGO/Au surface . The fabricated sensor exhibits an impressive LOD of 76 μM, with a retention of sensitivity for 0.1 mM of glucose after 36 days of >70% of the original sensitivity.…”

Section: Overview Of Carbon-based Voltammetric Biosensorsmentioning

confidence: 96%

See 1 more Smart Citation

Engineered Carbon-Nanomaterial-Based Electrochemical Sensors for Biomolecules

et al. 2015

View full text Add to dashboard Cite

The study of electrochemical behavior of bioactive molecules has become one of the most rapidly developing scientific fields. Biotechnology and biomedical engineering fields have a vested interest in constructing more precise and accurate voltammetric/amperometric biosensors. One rapidly growing area of biosensor design involves incorporation of carbon-based nanomaterials in working electrodes, such as one-dimensional carbon nanotubes, two-dimensional graphene, and graphene oxide. In this review article, we give a brief overview describing the voltammetric techniques and how these techniques are applied in biosensing, as well as the details surrounding important biosensing concepts of sensitivity and limits of detection. Building on these important concepts, we show how the sensitivity and limit of detection can be tuned by including carbon-based nanomaterials in the fabrication of biosensors. The sensing of biomolecules including glucose, dopamine, proteins, enzymes, uric acid, DNA, RNA, and H2O2 traditionally employs enzymes in detection; however, these enzymes denature easily, and as such, enzymeless methods are highly desired. Here we draw an important distinction between enzymeless and enzyme-containing carbon-nanomaterial-based biosensors. The review ends with an outlook of future concepts that can be employed in biosensor fabrication, as well as limitations of already proposed materials and how such sensing can be enhanced. As such, this review can act as a roadmap to guide researchers toward concepts that can be employed in the design of next generation biosensors, while also highlighting the current advancements in the field.

show abstract

Section: Overview Of Carbon-based Voltammetric Biosensorsmentioning

confidence: 94%

Section: Overview Of Carbon-based Voltammetric Biosensorsmentioning

confidence: 96%

Engineered Carbon-Nanomaterial-Based Electrochemical Sensors for Biomolecules

et al. 2015

View full text Add to dashboard Cite

show abstract

“…AuNPs, which can bond with the conjugated diene-based moieties of conducting polymer chains, also exhibit unique properties for speeding-up the polymerization of monomers [38,39]. Moreover, the composite materials of AuNPs and CHIT show the long lifetime usage of the biosensors [40].…”

Section: Introductionmentioning

confidence: 99%

A Highly Sensitive Amperometric Glutamate Oxidase Microbiosensor Based on a Reduced Graphene Oxide/Prussian Blue Nanocube/Gold Nanoparticle Composite Film-Modified Pt Electrode

Chen

et al. 2020

Sensors

View full text Add to dashboard Cite

A simple method that relies only on an electrochemical workstation has been investigated to fabricate a highly sensitive glutamate microbiosensor for potential neuroscience applications. In this study, in order to develop the highly sensitive glutamate electrode, a 100 µm platinum wire was modified by the electrochemical deposition of gold nanoparticles, Prussian blue nanocubes, and reduced graphene oxide sheets, which increased the electroactive surface area; and the chitosan layer, which provided a suitable environment to bond the glutamate oxidase. The optimization of the fabrication procedure and analytical conditions is described. The modified electrode was characterized using field emission scanning electron microscopy, impedance spectroscopy, and cyclic voltammetry. The results exhibited its excellent sensitivity for glutamate detection (LOD = 41.33 nM), adequate linearity (50 nM–40 µM), ascendant reproducibility (RSD = 4.44%), and prolonged stability (more than 30 repetitive potential sweeps, two-week lifespan). Because of the important role of glutamate in neurotransmission and brain function, this small-dimension, high-sensitivity glutamate electrode is a promising tool in neuroscience research.

show abstract

“…Noble metal particles (e.g., Au, Pt and Ag) have attracted considerable attention due to their unique physical and chemical properties, as well as their potential use in electronic, photonic, catalytic and biological applications [ 1 , 2 , 3 ]. In particular, Ag nanoparticles are some of the well-developed materials that have been used for applications in electrochemical detection because they are inexpensive relative to other noble metal materials and they possess good chemical and physical properties [ 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 ].…”

Section: Introductionmentioning

confidence: 99%

Ag Nanoparticles‐Modified 3D Graphene Foam for Binder‐Free Electrodes of Electrochemical Sensors

et al. 2017

View full text Add to dashboard Cite

Ag nanoparticles-modified 3D graphene foam was synthesized through a one-step in-situ approach and then directly applied as the electrode of an electrochemical sensor. The composite foam electrode exhibited electrocatalytic activity towards Hg(II) oxidation with high limit of detection and sensitivity of 0.11 µM and 8.0 µA/µM, respectively. Moreover, the composite foam electrode for the sensor exhibited high cycling stability, long-term durability and reproducibility. These results were attributed to the unique porous structure of the composite foam electrode, which enabled the surface of Ag nanoparticles modified reduced graphene oxide (Ag NPs modified rGO) foam to become highly accessible to the metal ion and provided more void volume for the reaction with metal ion. This work not only proved that the composite foam has great potential application in heavy metal ions sensors, but also provided a facile method of gram scale synthesis 3D electrode materials based on rGO foam and other electrical active materials for various applications.

show abstract

Investigation of the optimal weight contents of reduced graphene oxide–gold nanoparticles composites and theirs application in electrochemical biosensors

Cited by 18 publications

References 49 publications

Engineered Carbon-Nanomaterial-Based Electrochemical Sensors for Biomolecules

Engineered Carbon-Nanomaterial-Based Electrochemical Sensors for Biomolecules

A Highly Sensitive Amperometric Glutamate Oxidase Microbiosensor Based on a Reduced Graphene Oxide/Prussian Blue Nanocube/Gold Nanoparticle Composite Film-Modified Pt Electrode

Ag Nanoparticles‐Modified 3D Graphene Foam for Binder‐Free Electrodes of Electrochemical Sensors

Contact Info

Product

Resources

About