Investigation of the effect of tube motion in breast tomosynthesis: continuous or step and shoot?

Shaheen, Eman; Marshall, Nicholas; Bosmans, Hilde

doi:10.1117/12.877348

Cited by 26 publications

(34 citation statements)

References 23 publications

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“…Finally, the MTF degradation due to continuous x-ray tube motion during the scan of the projections should be simulated. 2,6,10,[32][33][34] While these subtleties of the acquisition geometry were not modeled directly in this paper, the simulations showed reasonably good agreement with the experimental results for the purpose of this work.…”

Section: Discussionsupporting

confidence: 73%

Oblique reconstructions in tomosynthesis. II. Super‐resolution

Acciavatti

Maidment

2013

Medical Physics

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Section: Discussionsupporting

confidence: 73%

Oblique reconstructions in tomosynthesis. II. Super‐resolution

Acciavatti

Maidment

2013

Medical Physics

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“…A blurred focal spot decreases the resolution of the system which can reduce microcalcification conspicuity. The "step and shoot" method has reduced focal spot blurring but at a cost of increased acquisition time 7 .…”

Section: Introductionmentioning

confidence: 99%

Optimizing configuration parameters of a stationary digital breast tomosynthesis system based on carbon nanotube x-ray sources

et al. 2012

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The stationary Digital Breast Tomosynthesis System (s-DBT) has the advantage over the conventional DBT systems as there is no motion blurring in the projection images associated with the x-ray source motion. We have developed a prototype s-DBT system by retrofitting a Hologic Selenia Dimensions rotating gantry tomosynthesis system with a distributed carbon nanotube (CNT) x-ray source array. The linear array consists of 31 x-ray generating focal spots distributed over a 30 degree angle. Each x-ray beam can be electronically activated allowing the flexibility and easy implementation of novel tomosynthesis scanning with different scanning parameters and configurations. Here we report the initial results of investigation on the imaging quality of the s-DBT system and its dependence on the acquisition parameters including the number of projections views, the total angular span of the projection views, the dose distribution between different projections, and the total dose. A mammography phantom is used to visually assess image quality. The modulation transfer function (MTF) of a line wire phantom is used to evaluate the system spatial resolution. For s-DBT the in-plan system resolution, as measured by the MTF, does not change for different configurations. This is in contrast to rotating gantry DBT systems, where the MTF degrades for increased angular span due to increased focal spot blurring associated with the x-ray source motion. The overall image quality factor, a composite measure of the signal difference to noise ratio (SdNR) for mass detection and the z-axis artifact spread function for microcalcification detection, is best for the configuration with a large angular span, an intermediate number of projection views, and an even dose distribution. These results suggest possible directions for further improvement of s-DBT systems for high quality breast cancer imaging.

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“…In this study, the focal spot motion blurring effect is eliminated by using the standard step-and-shoot x-ray tube motion. It was reported that such tube motion provides better visibility of microcalcifications due to the improved MTF at high spatial frequencies (Shaheen et al 2011).…”

Section: Impact Of Focal Spot Sizementioning

confidence: 99%

Three-dimensional cascaded system analysis of a 50µm pixel pitch wafer-scale CMOS active pixel sensor x-ray detector for digital breast tomosynthesis

et al. 2017

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Abstract. High-resolution, low-noise x-ray detectors based on the complementary metal-oxide-semiconductor (CMOS) active pixel sensor (APS) technology have been developed and proposed for digital breast tomosynthesis (DBT). In this study, we evaluated the three-dimensional (3D) imaging performance of a 50 μm pixel pitch CMOS APS x-ray detector named DynAMITe (Dynamic Range Adjustable for Medical Imaging Technology). The two-dimensional (2D) angle-dependent modulation transfer function (MTF), normalized noise power spectrum (NNPS), and detective quantum efficiency (DQE) were experimentally characterized and modeled using the cascaded system analysis at oblique incident angles up to 30°. The cascaded system model was extended to the 3D spatial frequency space in combination with the filtered back-projection (FBP) reconstruction method to calculate the 3D and in-plane MTF, NNPS and DQE parameters. The results demonstrate that the beam obliquity blurs the 2D MTF and DQE in the high spatial frequency range. However, this effect can be eliminated after FBP image reconstruction. In addition, impacts of the image acquisition geometry and detector parameters were evaluated using the 3D cascaded system analysis for DBT. The result shows that a wider projection angle range (e.g. ±30°) improves the low spatial frequency (below 5 mm -1 ) performance of the CMOS APS detector. In addition, to maintain a high spatial resolution for DBT, a focal spot size of smaller than 0.3 mm should be used.Theoretical analysis suggests that a pixelated scintillator in combination with the 50 μm pixel pitch CMOS APS detector could further improve the 3D image resolution. Finally, the 3D imaging performance of the CMOS APS and an indirect amorphous silicon (a-Si:H) thin-film A c c e p t e d M a n u s c r i p t transistor (TFT) passive pixel sensor (PPS) detector was simulated and compared.Keywords: CMOS active pixel sensor, x-ray detector, digital breast tomosynthesis, three-dimensional, cascaded system analysis, pixelated scintillator, detective quantum efficiency IntroductionHigh performance x-ray detectors based on the complementary metal-oxide-semiconductor ( Up to now, most studies focus on CMOS APS detector evaluation by measuring the one-dimensional (1D) or 2D modulation transfer function (MTF), noise power spectrum (NPS) and detective quantum efficiency (DQE) using a single x-ray projection at the zero-degree incident angle (perpendicular to the detector). Nevertheless, since DBT is a quasi-three-dimensional (3D) imaging technology, the DBT image quality is influenced by the system geometry and reconstruction algorithms (Sechopoulos 2013a(Sechopoulos , 2013b. Therefore, the 3D imaging performance should be evaluated for the CMOS APS detectors. However, it is difficult to empirically investigate the 3D image quality. To deal with this issue, the 3D cascaded system analysis for CMOS APS detectors was developed and is presented in this study.Cascaded system analysis can accurately model the signal and noise propagation and blurring within ...

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Investigation of the effect of tube motion in breast tomosynthesis: continuous or step and shoot?

Cited by 26 publications

References 23 publications

Oblique reconstructions in tomosynthesis. II. Super‐resolution

Oblique reconstructions in tomosynthesis. II. Super‐resolution

Optimizing configuration parameters of a stationary digital breast tomosynthesis system based on carbon nanotube x-ray sources

Three-dimensional cascaded system analysis of a 50µm pixel pitch wafer-scale CMOS active pixel sensor x-ray detector for digital breast tomosynthesis

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