Investigation of the effect of aromatherapy with Citrus aurantium blossom essential oil on premenstrual syndrome in university students: A clinical trial study

Heydari, Naval; Abootalebi, Maliheh; Jamalimoghadam, Neda; Kasraeian, Maryam; Emamghoreishi, Masoumeh; Akbarzadeh, Marzieh

doi:10.1016/j.ctcp.2018.04.006

Cited by 33 publications

(23 citation statements)

References 27 publications

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“…It also decreased the overall symptoms of premenstrual syndrome (PMS) in university students. It showed positive effects on the mood, blood pressure, pain, inflammation, bloating, and indigestion in addition to its anti-depressant effects [ 75 ]. Inhaling neroli odor enhances sexual desire [ 59 ].…”

Section: Biological Propertiesmentioning

confidence: 99%

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Biological Activities and Safety of Citrus spp. Essential Oils

Dosoky

Setzer

2018

IJMS

266

186

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Citrus fruits have been a commercially important crop for thousands of years. In addition, Citrus essential oils are valuable in the perfume, food, and beverage industries, and have also enjoyed use as aromatherapy and medicinal agents. This review summarizes the important biological activities and safety considerations of the essential oils of sweet orange (Citrus sinensis), bitter orange (Citrus aurantium), neroli (Citrus aurantium), orange petitgrain (Citrus aurantium), mandarin (Citrus reticulata), lemon (Citrus limon), lime (Citrus aurantifolia), grapefruit (Citrus × paradisi), bergamot (Citrus bergamia), Yuzu (Citrus junos), and kumquat (Citrus japonica).

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Section: Biological Propertiesmentioning

confidence: 99%

“…fumigatus , Fusarium graminearum , F . oxysporum , F. culmorum , and Alternaria alternata [ 20 , 53 , 75 , 79 ].…”

Section: Biological Propertiesunclassified

Biological Activities and Safety of Citrus spp. Essential Oils

Dosoky

Setzer

2018

IJMS

266

186

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“…It was also shown that aromatherapy with Citrus aurantium flower improved the symptoms of premenstrual tension [31].…”

Section: Premenstrual Syndrome (Pms)mentioning

confidence: 97%

Metrorrhagia iuvenilis and Premenstrual Syndrome as frequent problems of adolescent gynecology with aspects of diet therapy

Jarzabek-Bielecka

Mizgier²,

Kędzia

2019

Ginekol Pol

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Painful menstruation, premenstrual syndrome and metrorrhagia iuvenilis are one of the most common problems related to the sexual cycle in adolescent girls.Metrorrhagia iuvenilis is acyclic bleeding that occurs in adolescents and lasts from over 10 days even up to 3 months. These bleeds are very abundant and have a tendency to relapse. They cause anemia, and severe cases can be life-threatening.Premenstrual Syndrome (PMS) is a cluster of somatic, emotional and behavioural symptoms occurring in the luteal phase of the menstrual cycle. The aetiology of PMS remains unknown. According to strict diagnostic criteria, an estimated 2.5-5% of girls and women are affected by PMS. However, some researchers maintain that the symptoms of PMS may be prevalent in as many as 40-80% of girls and women.This article it has been discussed premenstrual syndrome and metrorrhagia iuvenilis and aspects related to dietotherapy were included.

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“…Additionally, researchers found that the bitter orange essential oils and their major component, limonene, exhibited significant antiulcerogenic and gastro-protective activities that can be considered as a promising pharmaceutical agent for the prevention of gastric ulcer (Moraes et al, 2009). Limonene is traditionally known as a fatigue recovery and a treatment for severe dermatitis (Baik et al, 2008) and depression (Heydari et al, 2018). Some studies have also found its antidepressant and anxiolytic effects on the central nervous system (Lizarraga-Valderrama, 2020).…”

Section: According To International Standard Organization and Europeanmentioning

confidence: 99%

Hydrodistillation ultrasound‐assisted green extraction of essential oil from bitter orange peel wastes: Optimization for quantitative, phenolic, and antioxidant properties

Heydari

Rostami

Mohammadi

et al. 2021

J. Food Process. Preserv.

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In this research, hydrodistillation ultrasonic-assisted green technique was applied to extract the essential oils from bitter orange peel. The effects of independent factors (volume/mass ratio (X 1 ), ultrasonic time (X 2 ) and hydrodistillation extraction time (X 3 )) on the quantitative, phenolic and antioxidant properties of essential oils were investigated. Linear and quadratic polynomial models with suitable ANOVA results (model p-values <0.0003, R 2 values of 0.84-0.95, adjusted R 2 values of 0.82-0.90, predicted R 2 values of 0.71-0.75, and lack of fit p-values >0.5) were used for fitting the responses. Two optimal extraction conditions for bitter orange peel essential oils were determined as follows: optimum responses (OR) with maximum essential oil volume (0.99 ml), maximum TPC (108.33 mg GAE/100 ml) and minimum IC 50 (251.56 µl) could be achieved at X 1 : 6.00 ml/g, X 2: 39.10 min and X 3 : 4.72 hr, and optimum phenolic compounds (OP) with maximum TPC of 190.75 mg GAE/100 ml could be obtained at X 1: 13.89 ml/gr, X 2: 3.75 min and X 3 : 4.92 hr. The most predicted values for optimum conditions were in good agreement with experimental data. The disk diffusion experiments showed high antimicrobial activities of the optimum essential oils against E. coli. The GC-MS results proved limonene was the main compound in both optimum essential oils. These bitter orange peel essential oils with suitable antioxidant and antimicrobial activities, and healthy compositions, could be considered as dietary and pharmaceutical supplements. Practical applicationsPeel wastes of bitter orange were used for green hydrodistillation ultrasonic-assisted extraction of essential oil. The optimum treatments indicated a good phenolic content with suitable antioxidant and antimicrobial activity. Limonene, a pharmaceutical monoterpene hydrocarbon, was the main component of the optimum essential oils.Therefore, these environmentally friendly extracted essential oils could potentially be applied in the food and pharmaceutical industries.

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Investigation of the effect of aromatherapy with Citrus aurantium blossom essential oil on premenstrual syndrome in university students: A clinical trial study

Cited by 33 publications

References 27 publications

Biological Activities and Safety of Citrus spp. Essential Oils

Biological Activities and Safety of Citrus spp. Essential Oils

Metrorrhagia iuvenilis and Premenstrual Syndrome as frequent problems of adolescent gynecology with aspects of diet therapy

Hydrodistillation ultrasound‐assisted green extraction of essential oil from bitter orange peel wastes: Optimization for quantitative, phenolic, and antioxidant properties

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