“…Another common derivatization reagent, N,O-bis(trimethylsilyl)trifluoroacetamide (BSTFA), converts hydroxyl, phenol, amine, and carboxylic acid groups to trimethylsilyl groups that are amenable to GC-MS analysis [20]. Another newly-developed derivatizing reagent involves the use of 5-chloro-2,2,3,3,4,4,5,5-octafluoro-1-pentyl chloroformate (ClOF-PCF), which enables the extraction and analysis of highly polar polycarboxylic and hydroxycarboxylic acids, as well as highly polar aldehydes and hydroxy aldehydes that are difficult to extract and measure using conventional methods [21].…”