Investigation of the anti-inflammatory effects of Paederia foetida

De, Subrata; Ravishankar, B; Bhavsar, G. C.

doi:10.1016/0378-8741(94)90113-9

Cited by 60 publications

(34 citation statements)

References 4 publications

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“…Drugs capable of stabilizing the lysosomal membrane can reduce the inflammation (Azza & Mohamed, 1995). An important mechanism of anti-inflammatory activity is due to the membrane stability-modulating effect (De et al, 1994). Cathepsin D has been found to play a role in the intracellular degradation of exogenous and endogenous proteins (Igdoura et al, 1995).…”

Section: Discussionmentioning

confidence: 99%

Brassica nigraplays a remedy role in hepatic and renal damage

Rajamurugan¹,

Arumugam²,

Selvaganabathy³

et al. 2012

Pharmaceutical Biology

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Section: Discussionmentioning

confidence: 99%

Brassica nigraplays a remedy role in hepatic and renal damage

Rajamurugan¹,

Arumugam²,

Selvaganabathy³

et al. 2012

Pharmaceutical Biology

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“…BMEL antagonised hyposaline-induced haemolysis of human red blood cells and an elevation of rat serum acid phosphatase activity, indicating the presence of a membrane stabilising activity. It also inhibited the elevation of serum orosomucoid levels in rats, suggesting the possibility of the presence of disease-modifying antirheumatic activity 22,23 .…”

Section: Antihyperglycemic Activitymentioning

confidence: 99%

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2013

IJPSR

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“…The plant is widely used by the tribal people of India for the treatment of gastrointestinal disorder, stomachache, enterosis, flatulence, gastromegaly, piles, rheumatism, ulcers, and toothache [2,3]. This species also shows antiinflammatory [2,4], anticancerous [2], and antidiarrheal properties [2,5]. Fresh leaves are reported to have antioxidant properties [2,6].…”

Section: Introductionmentioning

confidence: 99%

In vitro propagation by axillary shoot proliferation, assessment of antioxidant activity, and genetic fidelity of micropropagated Paederia foetida L.

2018

J App Biol Biotech

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An efficient plant regeneration protocol through axillary shoot proliferation of nodal explants of a valuable medicinal plant, Paederia foetida, has been developed. Highest shoot multiplication was found on Murashige and Skoog's (MS) medium supplemented with 3.0 mg/l N 6 -benzylaminopurine. Upscaling of shoots was accomplished from axenic nodal explants derived from primary in vitro regenerated shoots on fresh medium of the same composition. Thus, we could obtain 71-76 shoots, in vitro, starting from a single node within 11-12 weeks. These shoots were successfully rooted on ½ MS medium and acclimatized in soil. The biochemical fidelity was assessed by evaluating the antioxidant activities of leaves of both field grown mother plant and micropropagated plants. The antioxidant activities, as carried out by 2, 2-diphenyl-1-picrylhydrazyl and metal chelating assay, of leaves collected from micropropagated plants were at par with activity of leaves collected from mother plant. Most importantly, both sources have significant antioxidant activities compared to the standard, butylated hydroxytoluene. Further, genetic fidelity of the micropropagated plants with that of the mother plant was assessed by inter simple sequence repeats markers, and their true-to-type nature was confirmed on the basis of monomorphic banding profile. This protocol has potential to create large number of clonal plants with similar antioxidant activities as the natural plants and thus could be useful for drug research and development.

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Investigation of the anti-inflammatory effects of Paederia foetida

Cited by 60 publications

References 4 publications

Brassica nigraplays a remedy role in hepatic and renal damage

Brassica nigraplays a remedy role in hepatic and renal damage

Untitled

In vitro propagation by axillary shoot proliferation, assessment of antioxidant activity, and genetic fidelity of micropropagated Paederia foetida L.

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