Investigation of the Adaptation to Artificial Damping in Cerebellar Ataxia Using the Myohaptic Technology

Manto, Mario; Braber, N. Van Den; Meuleman, Jos; Lammertse, Piet; Grimaldi, Giuliana

doi:10.1007/978-3-642-03889-1_120

Cited by 2 publications

(2 citation statements)

References 11 publications

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“…We conducted a detailed single-subject experiment employing a real time mechatronic myohaptic unit device [27]. The subject (right-handed) was confortably seated with the dominant forearm fixed on the manipulandum.…”

Section: Introductionmentioning

confidence: 99%

“…We tested the effects of FES on the mechanical properties of the limb by measuring directly wrist stiffness before and during FES. We conducted a detailed single-subject experiment employing a real time mechatronic myohaptic unit device [ 27 ]. The subject (right-handed) was confortably seated with the dominant forearm fixed on the manipulandum.…”

Section: Introductionmentioning

confidence: 99%

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Augmented visual feedback counteracts the effects of surface muscular functional electrical stimulation on physiological tremor

Grimaldi¹,

Fernandez²,

Manto³

2013

Journal of NeuroEngineering and Rehabilitation

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BackgroundRecent studies suggest that surface muscular functional electrical stimulation (FES) might suppress neurological upper limb tremor. We assessed its effects on upper limb physiological tremor, which is mainly driven by mechanical-reflex oscillations. We investigated the interaction between FES and augmented visual feedback, since (a) most daily activities are performed using visual cues, and (b) augmented visual feedback exacerbates upper limb tremor.Methods10 healthy subjects (23.4 ± 7.7 years) performed 2 postural tasks with combinations of FES (4 sites; frequency of stimulation: 30 Hz; pulse width: 300 microsec; range of current delivered 10–34 mAmp) and augmented visual feedback.ResultsSpectral analysis of tremor showed a decrease of power spectral density to 62.18% (p = 0.01), of the integral in the 8-12 Hz frequency band to 57.67% (p = 0.003), and of tremor root mean square (RMS) to 57.16% (p = 0.002) during FES, without any changes in tremor frequency. Augmented visual feedback blocked the beneficial effect of FES, as confirmed by power spectral analysis (p = 0.01). We found a statistically significant interaction between augmented visual feedback and electrical stimulation (p = 0.039).ConclusionsAugmented visual feedback antagonizes the effects of FES on physiological tremor. The absence of changes of peak frequency argues against an effect of FES on mechanical properties of the upper limb.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Augmented visual feedback counteracts the effects of surface muscular functional electrical stimulation on physiological tremor

Grimaldi¹,

Fernandez²,

Manto³

2013

Journal of NeuroEngineering and Rehabilitation

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Topography of Cerebellar Deficits in Humans

Grimaldi¹,

Manto²

2011

Cerebellum

144

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The cerebellum is a key-piece for information processing and is involved in numerous motor and nonmotor activities, thanks to the anatomical characteristics of the circuitry, the enormous computational capabilities and the high connectivity to other brain areas. Despite its uniform cytoarchitecture, cerebellar circuitry is segregated into functional zones. This functional parcellation is driven by the connectivity and the anatomo-functional heterogeneity of the numerous extra-cerebellar structures linked to the cerebellum, principally brain cortices, precerebellar nuclei and spinal cord. Major insights into cerebellar functions have been gained with a detailed analysis of the cerebellar outputs, with the evidence that fundamental aspects of cerebrocerebellar operations are the closed-loop circuit and the predictions of future states. Cerebellar diseases result in disturbances of accuracy of movements and lack of coordination. The cerebellar syndrome includes combinations of oculomotor disturbances, dysarthria and other speech deficits, ataxia of limbs, ataxia of stance and gait, as well as often more subtle cognitive/behavioral impairments. Our understanding of the corresponding anatomo-functional maps for the human cerebellum is continuously improving. We summarize the topography of the clinical deficits observed in cerebellar patients and the growing evidence of a regional subdivision into motor, sensory, sensorimotor, cognitive and affective domains. The recently described topographic dichotomy motor versus nonmotor cerebellum based upon anatomical, functional and neuropsychological studies is also discussed.

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Investigation of the Adaptation to Artificial Damping in Cerebellar Ataxia Using the Myohaptic Technology

Cited by 2 publications

References 11 publications

Augmented visual feedback counteracts the effects of surface muscular functional electrical stimulation on physiological tremor

Augmented visual feedback counteracts the effects of surface muscular functional electrical stimulation on physiological tremor

Topography of Cerebellar Deficits in Humans

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