Investigation of regurgitation and other symptoms of gastroesophageal reflux in Indonesian infants

Abstract

Regurgitation occurs frequently in Indonesian infants, and is a frequent cause of concern to mothers.

Natural course of gastroesophageal reflux disease during infancy - six-month follow-up

“…[2][3][4][5] However, published data to support this hypothesis are limited and few available data tend to suggest the contrary to common belief that infant…”

“…This agrees with the findings of other studies which show that regurgitation disappear almost completely at about the age of 1 year. [2][3][4][5] Regurgitation in infancy is the only symptomatic GER that is considered physiological as it believes to be benign and does not need any treatment or medical attention. 1,11 Summary of results from those studies is shown in Table 3.…”

“…Parents of infants in this study concerning regurgitation as problems was low compare to other studies. 2,5 Practicing physician can also obtain information on clinical course as guidance to monitor infants appropriately with this problem for later difficulties. Majority of infants stopped regurgitating by the age of 13-14 months, However, those with frequent regurgitation (>90 days) were more likely to have GER symptoms at 9 years of age.…”

“…1 It occurs frequently during the first year of life with the peak incidence of 65-86.9% at 1-4 months of age and usually resolves spontaneously by 6 to 12 months of age. [2][3][4][5] Regurgitation may occur in normal infants 6 but may be accompanied by complications such as weight loss, esophagitis, anemia, or stricture; in these situations the infants are defined as having GER disease (GERD). 7 There is a continuum between normal infants with GER and those with GERD, so there is no clear cut-off point separating physiological from pathological reflux.…”

Prevalence of Gastroeusophageal Reflux Disease and Reflux-Related Symptoms in Infants; Development and Validation of a Novel Gastroesophageal Reflux Disease Questionnaire to Use for Turkish Infants (SM Reflux Questionnaire)

“…It was reported to be more common in Western countries than Eastern countries (5,6). In addition; recent studies in children have suggested that genetic factors may play a role in GERD, and thus it is claimed that its prevalence and severity might vary according to racial and ethnic background (7). The prevalence of GER (especially with regurgitation) in American infants was found to be 50% in 0 to 3-month-olds, 67% in those aged 4 to 6 months, 21% in 7 to 9-montholds and 5% in infants of 10 to 12 months; whereas it was found lower in Thai infants (2,5).…”