Investigation of microfluidic co-flow effects on step emulsification: Wall contact angle and critical dimensions

Lian, Jiaoyuan; Zheng, Shuilin; Liu, Cong; Xu, Zhongbin; Ruan, Xiangyan

doi:10.1016/j.colsurfa.2019.123733

Cited by 19 publications

(5 citation statements)

References 39 publications

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“…Another study showed that both ultrasound and high-pressure treatment had a stable emulsion for more than 30 days post-processing making it feasible in improving the performance and estimating shelf life in the food and beverage industry (Li and Xiang 2019 ). In another study, a co-flowing step emulsification strategy was adopted for in-line control of microdroplets (Lian et al 2019 ). The study considered a mathematical approach using computational fluid dynamics for analyzing droplet size, generation, and initial pressure as well as providing predictive equations.…”

Section: Application Of Lab-on-a-chip Devices In the Food Industrymentioning

confidence: 99%

Lab-on-a-chip technologies for food safety, processing, and packaging applications: a review

Sridhar

Kapoor

Kumar³

et al. 2021

Environ Chem Lett

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Section: Application Of Lab-on-a-chip Devices In the Food Industrymentioning

confidence: 99%

Lab-on-a-chip technologies for food safety, processing, and packaging applications: a review

Sridhar

Kapoor

Kumar³

et al. 2021

Environ Chem Lett

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“…Of course we cannot ignore the in uence of geometry on the droplet generation process, such as the inner diameter of the dispersed phase nozzle, the distance between the tip of the nozzle and the continuous phase passageway, the length of the platform, and the characteristics of the wall, all of which affect the droplet generation process [21,22]. Viscosity and interfacial tension are also important in uencing factors, but droplet size strongly depends on the ow rate.…”

Section: Introductionmentioning

confidence: 99%

Numerical simulation of droplet formation in a Co-flow microchannel capillary device

Zhang,

Ma,

Song

et al. 2024

Preprint

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In this article, a numerical simulation of the droplet formation in a Co-flow microchannel capillary device, and the influencing factors of the formation of droplets are studied. The level set method is used to track the two-phase interface and droplet formation. In the Co-flow focusing device, we explored the influencing factors of the size of the generated droplets. The results show that as the ratio of the dispersed phase velocity to the continuous phase velocity increases, the volume of the generated droplets decreases significantly, the droplet generation frequency increases significantly, and the pressure of the droplets at the centerline decreases significantly. As the viscosity of continuous phase increases, the volume of generated droplets decreases significantly, the frequency of droplet generation increases significantly, and the pressure of droplets at the centerline decreases significantly. As the contact angle between the continuous phase and the wall increases, the volume of the generated droplets increases, but the volume increase is not obvious enough, the droplet generation frequency becomes smaller, and the droplet pressure at the centerline decreases. As the increase of interfacial tension, the volume of droplet generation increases significantly, the frequency of droplet generation decreases significantly, and the pressure of droplet at the centerline increases significantly.

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“…[3,4] The number, position and size of the microcapillaries could be adjusted through changing the structure of the die mold and altering the process parameters. Since first reported, MCFs have been employed in various applications of DOI: 10.1002/mame.202100958 nanoparticle capture, [5][6][7] droplet generation, [8,9] micromixing, [10] chemical reaction, [11] heat collection, [12,13] and immunoassays. [14][15][16] Recently, Zhao et al successfully fabricated foamed MCFs which had a dual network of interconnected pores and internal channels by supercritical carbon dioxide foaming.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Precise Control of Microcapillary Size in Microcapillary Films by Liquid‐Assisted Extrusion

Liu

Zheng

et al. 2022

Macro Materials & Eng

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Microcapillary films (MCFs) are plastic films with an array of microcapillaries, which have been widely applied in microfluidics and bioanalytical techniques. However, the precise control of microcapillary size is still a problem hindering the industrial applications of MCFs because the high size uniformity of microcapillaries ensures the production of homogeneous droplets and the robust performance of immunoassays. Here, a novel approach is provided to precisely adjust the size of microcapillaries by liquid‐assisted extrusion and to investigate the combined effects of extrusion, drawing and liquid injection on the microcapillary size. Compared with gas‐assisted extrusion, the size uniformity is improved by at least 5% for 89% experiments and 10% for 42% experiments. Therefore, this method facilitates MCFs’ applications in droplet microfluidics and biotechnologies.

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Investigation of microfluidic co-flow effects on step emulsification: Wall contact angle and critical dimensions

Cited by 19 publications

References 39 publications

Lab-on-a-chip technologies for food safety, processing, and packaging applications: a review

Lab-on-a-chip technologies for food safety, processing, and packaging applications: a review

Numerical simulation of droplet formation in a Co-flow microchannel capillary device

Precise Control of Microcapillary Size in Microcapillary Films by Liquid‐Assisted Extrusion

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