Investigation of Helicobacter pylori Infection Prevalence Using C14-Urea Breath Test and Its Relationship with Socioeconomic, Family, and Environmental Factors

Abstract

Studies of Helicobacter pylori show that it is the cause of duodenal ulcers, gastric ulcers, gastric adenocarcinoma, and primary gastric B cell lymphoma (MALT lymphoma). Helicobacter pylori is the first established carcinogenic bacterium. Thus, it is very important to diagnose and treat H. pylori infection and determine the effectiveness of eradication treatments. The C14-urea breath test (C14-UBT) is a rapid, well-tolerated, non-invasive method to detect H. pylori, with a sensitivity of 94.9% and specificity of 100% (1). We employed C14-UBT to investigate the prevalence of H. pylori infection and evaluate its association with epidemiological, demographic, socioeconomic, and environmental factors of patients.

Prevalence of Helicobacter pylori infection in adult patients with dyspeptic symptoms in Abdi Waluyo Hospital Jakarta from January 2017 to December 2019

“…The difference was statistically significant between pediatrics and the other age groups (p = 0.043). A positive correlation was found between C14-UBT positivity and age (r = 0.76) 12 In our study, the prevalence of patient with H. pylori positive are increase every year since 2017 to 2019. The rate of Gatritis is significantly increase every year and the rate of gastric ulcer and gastric cancer in patient is fluctuating.…”