Investigating internal architecture effect in plastic deformation and failure for TPMS-based scaffolds using simulation methods and experimental procedure

Failure mechanisms of additively manufactured porous biomaterials: Effects of porosity and type of unit cell

“…As previously stated in (Kadkhodapour, Montazerian, & Raeisi, 2014), Diamond lattice structure is formed of 45° oriented plates placed parallel to sides of an internal pyramid which are connected with -45° struts at their joints. At the onset of plastic deformation (Fig.…”

Multiphoton Direct Laser Writing and 3D Imaging of Polymeric Freestanding Architectures for Cell Colonization

“…As evidenced by the comparison between the computer aided design (CAD) design (Figure A) and the scanning electron microscopy (SEM) of the actual 3D architecture (Figure B), the direct laser writing technique features a high level of accuracy and reproducibility of the scaffold components at the micrometer‐scale level. Further, in Figure D we show the effect of the adopted slicing and hatching fabrication configurations (Experimental Section) on the nanofeatures morphology whose resolution (≈200 nm) is much higher compared to other 3D fabrication technologies . The rationale behind the choice of the adopted spacing and of the cylindrical subunit size parameters was to allow at the same time both an easy penetration of the neuroblastoma cell line and an optimal 3D imaging accuracy overwhelming the material intrinsic autofluorescence.…”

“…Since 1984, year in which the first patent about rapid prototyping based on stereolithography was filed, the evolution of 3D fabrication techniques has enormously evolved and found many applications in the biomedical area of research such as prosthetic implants, organ printing, scaffolds for tissue engineering applications, and 3D models for disease/drug investigation . The main techniques employed for the realization of 3D architectures range from fused deposition modeling/extrusion printing, electrospinning, ink‐jet printing, polyjet technology, selective laser sintering, 3D bioprinting, laser‐assisted printing systems to bottom‐up approaches based on macroscopic supramolecular assembly . From a technological point of view, although all these 3D fabrication approaches show great potential, many of them still present evident limitations when the target is to provide a 3D architecture characterized at the same time by high feature accuracy (nanometer scale), short fabrication time and versatility in terms of biocompatible materials that can be integrated in the fabrication setup.…”

An advanced multi-morphology porous scaffold design method using volumetric distance field and beta growth function

“…It was found that P and IWP structures are close to stretch dominated while D and FRD structures are more close to bending dominated. 33,34 The proposed method can easily combine stretch dominated structure and bending dominated structure to provide two deformation patterns simultaneously, as depicted in Fig. 19.…”

“…Recently, many researchers started to study the effect of internal pore architecture of TPMS-based scaffolds on the mechanical and physical properties by using FEA. [33][34][35] It was shown that mechanical and biological behavior of TPMS-based In addition, they showed that the level of stress concentration at lower volume fractions of P-surface structure dramatically increases due to heterogeneous mass distribution and thin ligaments between the elements. 34 FEA can provide useful guidelines for designing optimized hybrid scaffolds according to the required application.…”