Investigating Fluid Parameters in Nanofiber Biomaterial Fabrication using Electrospinning

Abstract

Fabricating nanofiber biomaterial using electrospinning is difficult due to its bioactive characteristics. Even though electrospinning is mentioned as the most well-established approach to produce nanofiber, it is undeniable that fluid factors involved in determining the product result. In this research, three influenced factors including viscosity, conductivity, and surface tension are investigated in the system of Biomaterial Composite that contains mixed Chitosan-Pectin material blended to the Polyvinyl Alcohol (PVA). Various concentrations were made up to create an assorted liquid profile to some extent influencing fluid characteristic which affecting fabrication result. This research also analyzed the interaction between group materials using Fourier Transform Infra-Red (FTIR). Moreover, bead and spray phenomena which are commonly occurred in the process of fabrication are also deliberated correlating with fluid parameters. This experiment revealed that the range of the ability of the composite solution that can be fabricated was from 90/10 to 60/40 with the average diameter size for each composition are 90/10 = 155,39 ± 43,68 nm, 80/20 = 99,03± 26.01 nm, 70/30 = 111,387 ± 50,06 nm, and 60/40 = 107,06 ± 47,36 nm. Regarding fluid characteristics, the discrepancy related to the effect of viscosity to nanofiber size has occurred due to the nonuniform shape and type that affected the average size of the nanofiber. Meanwhile, the conductivity parameter found as the main reason related to the limited ability of the electrospinning process. Furthermore, the surface tension parameters noted as a factor that influencing droplet and beads formation.

Insight into aligned nanofibers improving fuel cell performances: strategies, rationalities, and opportunities

“…Among these three parameters, the fluid factor consists of viscosity, conductivity, and surface tension, which is the most influential parameter, and thus must be appropriately considered. 35 Firstly, viscosity is the parameter that can affect the size and shape of the fibre product. This parameter is an important factor in the fabrication process, which can lead to the presence of solution in the fibre.…”

“…Among these three parameters, the fluid factor consists of viscosity, conductivity, and surface tension, which is the most influential parameter, and thus must be appropriately considered. 35…”

Development of Low-Cost Electrospinning to Fabricate Structured Nanofiber for Biomedical Designs with Manageable Flowrate and Voltage

“…Meanwhile, for mass production for company requirements, the cheapest price is 2.5 billion rupiahs or 170.500$. On the other side, some universities testified assembling their electrospinning and making modifications according to their research needs [6] [7]. Based on the reports, it can be claimed that building individual electrospinning devices can save up to 95% of the budget.…”