Invertebrate glia

Radojcic, Tricia; Pentreath, V. W.

doi:10.1016/0301-0082(79)90002-9

Cited by 83 publications

(107 citation statements)

References 176 publications

Supporting

Mentioning

105

Contrasting

Order By: Relevance

“…Depending on the species and location, the invertebrate glia show a variety of morphologies and functions. Among invertebrate phyla, glial cells are absent from the Mesozoa, Porifera, Coelenterata, and Echinodermata but are present in Platyhelminthes, Aschelminthes, Annelida, Arthropoda, and Mollusca (reviewed in Radojcic & Pentreath 1979). The close glial ensheathment of neurons underlie neuron-glial interactions in mollusc, arthropod, and annelid ganglia (Figure 1).…”

Section: Neuron-glial Interactions In Blood Barriers Of Invertebrtaesmentioning

confidence: 99%

Neuron-Glial Interactions in Blood-Brain Barrier Formation

Banerjee

Bhat

2007

Annu. Rev. Neurosci.

169

140

View full text Add to dashboard Cite

The blood brain barrier (BBB) evolved to preserve the microenvironment of the highly excitable neuronal cells to allow for action potential generation and propagation. Intricate molecular interactions between two main cell types, the neurons and the glial cells, form the underlying basis of the critical functioning of the nervous system across species. In invertebrates, interactions between neurons and glial cells are central in establishing a functional BBB. However, in vertebrates, the BBB formation and function is coordinated by interactions between neurons, glial cells, and endothelial cells. Here we review the neuron-glial interaction-based blood barriers in invertebrates and vertebrates and provide an evolutionary perspective as to how a glial-barrier system in invertebrates evolved into an endothelial barrier system. We also summarize the clinical relevance of the BBB as this protective barrier becomes disadvantageous in the pharmacological treatment of various neurological disorders.

show abstract

Section: Neuron-glial Interactions In Blood Barriers Of Invertebrtaesmentioning

confidence: 99%

Neuron-Glial Interactions in Blood-Brain Barrier Formation

Banerjee

Bhat

2007

Annu. Rev. Neurosci.

169

140

View full text Add to dashboard Cite

show abstract

“…Accordingly, GFAP-like immunoreactivity has been shown in enteric glia (Jessen and Mirsky, 1980), Schwann cells of unmyelinated peripheral nerve fibers (Yen and Fields, 1981;Dahl et al, 1982), lens epithelium (Hatfield et al, 1984), and Kupffer cells in the liver (Gard et al, 1985), among others. Filaments of morphological structure similar to the intermediate glial filament have been reported in the glial cells of many mammals, birds, reptiles, fishes (Dahl et al, 1985), and in some invertebrates such as annelids and mollusks (see Radojcic and Pentreath, 1979;Cardone and Roots, 1990;Riehl and Schlue, 1998;Dos Santos et al, 2002).…”

Section: Introductionmentioning

confidence: 99%

“…In this huge group of animals, they are in general classified according to morphological, functional and positional criteria (Radojcic and Pentreath, 1979;Pentreath, 1987;. Therefore, particular labels that enhance specific aspects of glial cells could be used as additional tools for their characterization.…”

Section: Introductionmentioning

confidence: 99%

“…Because of the main role that has been attributed to GFAP in astrocytes, as a cytoskeleton stabilizer (see Rutka et al, 1997), and to the presence of this protein in few invertebrates (see Radojcic and Pentreath, 1979;Cardone and Roots, 1990, Riehl and Schlue, 1998, Dos Santos et al, 2002, we wanted to search for the presence of GFAP-like proteins in crustaceans.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Glial fibrillary acidic protein (GFAP)‐like immunoreactivity in the visual system of the crab Ucides cordatus (Crustacea, Decapoda)

Silva¹,

Corrêa²,

Tortelote³

et al. 2004

Biology of the Cell

View full text Add to dashboard Cite

Glial fibrillary acidic protein (GFAP) is the main intermediate filament protein used as a marker for the identification of astrocytes in the central nervous system of vertebrates. Analogous filaments have been observed in the glial cells of many mollusks and annelids but not in crustaceans. The present study was carried out to identify by light microscopy immunohistochemistry, immunoelectronmicroscopy and immunoblotting, GFAP-like positive structures in the visual system of the crab Ucides cordatus as additional information to help detect and classify glial cells in crustaceans. Conventional electron microscopy, light microscopy of semithin sections and fluorescence light microscopy were also employed to characterize cells and tissues morphology. Our results indicated the presence of GFAP-like positive cell processes and cell bodies in the retina and adjoining optic lobe. The labeling pattern on the reactive profiles was continuous and very well defined, differing considerably from what has been previously reported in the central nervous system of some mollusks, where a diffuse spotted fluorescence pattern of labeling was observed. We suggest that this glial filament protein may be conserved in the evolution of the invertebrate nervous systems and that it may be used as a label for some types of glial cells in the crab.

show abstract

“…However, there have been debates on the ultrastructural criteria of glial cells in the nervous system of the platyhelminths, flatworms (Radojcic & Pentreath, 1979;Biserova, 2008), although the functional significance of glial cells in a way similar to that in verterbrates has been well stated in the nematode, next higher phylum to the platyhelminths, represented by C. elegans (Oikonomou & Shaham, 2011). This debate is mainly due to the fact that sufficient ultrastructural information has so far been lacking about the nervous system of the platyhelminths, especially of OV (Leksomboon et al, 2012a), in spite that there have been ample numbers of immuno-fluorescence microscopic studies of the peripheral and central nervous systems in the platyhelminths in which numerous neuron somata are clearly demonstrated in the immuno-light microscopy (Barton et al, 1993;Gustafsson et al, 2001Gustafsson et al, , 2002Leksomboon et al, 2012b).…”

Section: Discussionmentioning

confidence: 99%

Identification in Immuno-Electron Microscopy of Solitary Multi-Polar Peripheral Neurons of Adult Opisthorchis viverrini by Antibody Against Rat Diacylglycerol Kinaseζ

et al. 2016

View full text Add to dashboard Cite

SUMMARY:By utilizing the antibody for rat DGKζ a substantial number of immunopositive cells were found in the OV (Opisthorchis viverrini). The immunopositive cells appeared solitarily and they were distributed rather symmetrically to the longitudinal axis of the OV. Some of them were located in close proximity to internal organs such as uterus, ovary, testes, vitelline glands and guts. The immunostained cells extended tapering processes horizontally or obliquely to the OV longitudinal axis. In immuno-electron microscopy, the immunopositive cells were characterized by intensely immunostained mitochondria and weakly immunostained cytoplasm and immunonegative chromatin-poor nucleus. Vacuoles of various sizes without the immunoreactivity were also contained in the cells. Thin cellular processes without the immunoreactivity were found to enclose thinly the entire surfaces of the immunostained cells and processes, and they were in continuity with the interstitial partition-like processes which contained nuclei and aggregation of microfibrils at some distance from the cytoplasmic envelopes. The present finding suggests the possibility that the immunostained cells were peripheral neurons enveloped by peripheral glia and that the glia are of mesenchymal origin because of their cytoplasmic continuity to the interstitial partition-like processes. The motor or sensory nature of the neurons remains to be elucidated.

show abstract

Invertebrate glia

Cited by 83 publications

References 176 publications

Neuron-Glial Interactions in Blood-Brain Barrier Formation

Neuron-Glial Interactions in Blood-Brain Barrier Formation

Glial fibrillary acidic protein (GFAP)‐like immunoreactivity in the visual system of the crab Ucides cordatus (Crustacea, Decapoda)

Identification in Immuno-Electron Microscopy of Solitary Multi-Polar Peripheral Neurons of Adult Opisthorchis viverrini by Antibody Against Rat Diacylglycerol Kinaseζ

Contact Info

Product

Resources

About

Invertebrate glia

Cited by 83 publications

References 176 publications

Neuron-Glial Interactions in Blood-Brain Barrier Formation

Neuron-Glial Interactions in Blood-Brain Barrier Formation

Glial fibrillary acidic protein (GFAP)‐like immunoreactivity in the visual system of the crab Ucides cordatus (Crustacea, Decapoda)

Identification in Immuno-Electron Microscopy of Solitary Multi-Polar Peripheral Neurons of Adult Opisthorchis viverrini by Antibody Against Rat Diacylglycerol Kinase&#950;

Contact Info

Product

Resources

About

Identification in Immuno-Electron Microscopy of Solitary Multi-Polar Peripheral Neurons of Adult Opisthorchis viverrini by Antibody Against Rat Diacylglycerol Kinaseζ