Invasive Papillary Breast Carcinoma

Bhosale, Suresh; Kshirsagar, Ashok Y; Sulhyan, Soniya R; Jagtap, Sunil Vitthalrao; Nikam, Yogesh P

doi:10.1159/000321270

Cited by 11 publications

(17 citation statements)

References 2 publications

(6 reference statements)

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“…The target group is postmenopausal females and males are rarely affected (3). Because of the central location of this tumor, symptoms usually include nipple discharge or bleeding as well as palpable mass (4).…”

Section: Introductionmentioning

confidence: 99%

Intracyctic Papillary Carcinoma of the Breast: Report of a Rare Case and Literature Review

et al. 2017

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Introduction: We present a rare case of breast papillary carcinoma associated with intracystic component in a woman with a long history of autoimmune hypothyroidism and multiple sclerosis. Case Presentation: The patient was a 59-year-old woman presented with complaints of pain and swelling in her right breast. She was a known case of autoimmune hypothyroidism since 20 years and secondary progressive multiple sclerosis since 13 years ago. She had received frequent interferon, corticosteroid and cytotoxic therapy for her multiple sclerosis. On imaging studies, there were multiple large cystic-solid lesions in the right breast and with presumptive diagnosis of infectious collection or phyllodes tumor, she finally underwent simple mastectomy. On gross pathological evaluation, a large multi-loculated cyst filled with blood clots and necrotic debris was identified. In serial sections, a 7 cm solid tumoral mass with papillary projections protruding into the cyst cavity was seen. Although the gross appearance of the lesion resembled an angiosarcoma accompanied by cystic hemorrhagic necrosis, after the microscopic evaluation of the specimen, papillary breast carcinoma associated with intracyctic component was finally diagnosed. Conclusions:The aim of this study was to describe a rare variant of invasive breast cancer presenting with a large solid-cyctic mass in a woman with long standing autoimmune disorders.

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Section: Introductionmentioning

confidence: 99%

Intracyctic Papillary Carcinoma of the Breast: Report of a Rare Case and Literature Review

et al. 2017

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“…TREATMENT-Complete excision of the lesion ,total or partial mastectomy is the treatment of choice for SPC. Data is not available to evaluate the role of sentinel lymph node biopsy in SPC (14,15).…”

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confidence: 99%

“…Florid ductal hyperplasia has no fibrovascular core, palisading of cells or presence of mucin. Mitotic activity is not a feature of florid ductal hyperplasia (2,14). Lobular neoplasia is shows discohesion of cells and lacks papillary fronds.2.…”

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confidence: 99%

“…Low grade DCIS does not have the morphology like that of SPC, or the cells with plasmacytoid or spindle cell appearance. The presence of mucin, branching fibrovascular stroma, and ducts encompassed by fibrosis are not features of DCIS (2,14).…”

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confidence: 99%

“…In the absence of invasion, SPCs have a better outcome. For the cases associated with invasion, prognosis will depend upon the invasive component of the tumor (14). In these cases, metastasis can occur without axillary lymph node involvement (1,14).…”

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confidence: 99%

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