Introduction of effective biological stimulants affecting lactating cows: Using cyanoform

The suckling period in sows is a very important stage in the realization of their productivity. In the course of its implementation, hematological parameters are of great importance, but their normal level has not been fully clarified, especially taking into account the conditions in which animals are kept. In sows, which are located in central Russia, the content of total protein and albumin in the blood gradually increased during suction. They also have a slight decrease in the content of urea, which indicated a tendency to inhibition of protein metabolism. During the entire sucking period, a slight increase in the amount of triglycerides and cholesterol developed in the blood of the examined animals, while the glucose content remained unchanged. During the observation, the biological activity of alkaline phosphatase remained unchanged in sows and the enzymatic properties of gamma-glutamyltransferase slightly decreased. At the same time, they developed a weakening of the activity of enzymes in the blood, including transaminases and creatine kinase. The amounts of traceable substances and activity levels of individual enzymes identified during the observation should be considered optimal for sows kept during suckling at pig farms located in central Russia.

Section: Resultsmentioning

confidence: 96%

Physiological features of hematological parameters of sows during suckling, kept in the ecological conditions of central Russia

Tkacheva

2023

“…A decrease in the amount of von Willebrand factor in the blood of cows was indicated by an increase in the time of platelet aggregation caused by ristomycin, which is able to affect platelets almost in the same way as molecules that are part of the vascular subendothelium [14]. When interacting with collagen and glycoprotein Ib, the von Willebrand factor located on the platelet surface creates a connection between the platelet and the vascular subendothelium [15]. Considering the obtained result, it should be considered that under conditions of pregnancy, the density of receptors on bovine platelets capable of binding von Willebrand factor in the blood decreases [16].…”

Section: Research Results and Discussionmentioning

confidence: 99%

Physiological features of primary hemostasis in cows during pregnancy kept in the conditions of central Russia

Zavalishina

2023

The functional parameters of blood vessels and platelets are of great biological importance throughout the life of the animal. Their activity is designed to provide the necessary level of rheological properties of blood in vessels of small and medium caliber. In the work carried out in cows during pregnancy, a decrease in the sensitivity of platelets to stimulators of platelet activity was revealed. This, apparently, leads them during pregnancy to curb adhesion and aggregation of platelets. A decrease in the hemostatic properties of platelets in cows during pregnancy is largely due to a weakening of the expression on their surface of receptors that can bind to aggregation inducers and fibrin, a decrease in thromboxane synthesis, inhibition of myosin formation and actin formation, a weakening of the secretory release of adenosine phosphates from platelet granules and a decrease in the level of activity in the blood cells. plates of phospholipases A2 and C. Strengthening in cows during pregnancy of the disaggregation properties of blood vessels is associated with an intensification of the synthesis in their walls of deaggregants of prostacyclin and nitric oxide, which enhance trophism in fetal tissues. Changes in the activity of primary hemostasis that develop in cows as pregnancy proceeds are associated with a decrease in the functional characteristics of platelets and an increase in the functionality of the vascular element of hemostasis, providing optimal conditions for capillary perfusion and active anabolism in the growing fetus.

“…This may explain why the synthesis of peroxides is higher than the functional capabilities of the anti-oxidation system. The state of oxidative stress can occur as a result of a strong release of oxidants and/or a decrease in antioxidant protection [30]. Having conducted our own research, it is necessary to emphasize the great importance of the level of oxidative processes and metabolic processes in cows after calving and consider these parameters as important for assessing the metabolic status.…”

Section: Discussionmentioning

confidence: 99%

Physiological changes in hematological parameters of black-and-white cows at the beginning of lactation

Fayzullina

2023

The onset of lactation can affect the condition of cows, affecting the metabolic processes throughout the body and hematological parameters. The blood parameters of high-milk cows after the first and after the second calving were evaluated in the work. 47 fully healthy pregnant cows were selected 3 weeks before the expected calving. These included first-heifers and re-calving purebred cows of a black-and-white breed. The animals were divided into two groups according to the number of pregnancies available in their lives: the group of first-born heifers consisted of 22 heads, the group of re-calves included 25 heads. The examination was performed 3 weeks before calving and 3 weeks after calving with taking blood samples. The first heifers after calving showed a decrease in the concentration of glucose, total protein and albumin with a significant increase in the concentrations of malondialdehyde, non-esterified fatty acids and globulin compared with the first study. Re-calved cows showed a significant decrease in the amount of glucose, total protein and albumin in the blood, combined with a significant increase in cholesterol and malondialdehyde levels compared to their pre-calving values. In re-calving cows, a significant decrease in non-esterified fatty acids was noted in comparison with calved first-calf cows. During the transition phase, control of the main hematological parameters is necessary for the timely prevention of pathology in first-heifers and re-lost cows.