Intravenous thrombolysis in patients aged more than 80 years in the three rural hospitals in southeast Poland: An observational study

Abstract

Older age affected the increased times for pre- and in-hospital procedures in rural patients with AIS. Older patients should not be denied the chance to benefit from IV-thrombolysis, but because of the higher mortality, the application of this therapy should be carefully decided on.

Association of time on outcome after intravenous thrombolysis in the elderly in a telestroke network

“…A previous observational study reported delayed treatment times for patients aged 80 years and over. 14 In our study, however, the majority of patients, both elderly and not elderly, were treated within less than 180 minutes from stroke onset. There was no significant difference in treatment times for pre- and in-hospital procedures for elderly and not elderly patients.…”

“…An observational study found that age affected increasing times for pre- and in-hospital procedures. 14…”

Outcome of intravenous recombinant tissue plasminogen activator for acute ischemic stroke in patients aged over 80 years

“…The first outcome of interest was the modified Rankin Scale (mRS) score at the 3‐month follow up categorized in two groups: favorable (score: 0–2) and unfavorable (score >2) in accordance with recent studies about ischemic stroke in the elderly . The secondary outcomes were ICH and discharge site.…”

“…The National Institute of Neurological Disorders and Stroke study included very few elderly patients, the mean age being under 70 years . A few observational studies have shown that, in comparison with younger patients, older patients experienced more complications and had a less favorable outcome . As a result, this reinforced the reluctance on behalf of the practitioner to consider recombinant tissue plasminogen activator (rt‐PA) therapy as an option when faced with an ischemic stroke in patients aged ≥80 years.…”