Intravenous immunoglobulin therapy in immunoglobulin A vasculitis with gastrointestinal tract involvement

Multidrug-resistant IgA Vasculitis with Gastrointestinal Symptoms Successfully Treated with Intravenous Cyclophosphamide and Maintained with Mycophenolate Mofetil

“…Decreased plasma levels of FXIII have been suggested as a prognostic factor for GI symptoms in IgAV patients, and FXIII replacement therapy has been shown to be effective ( 12 ). Intravenous immunoglobulin (IVIG) and plasmapheresis have also been reported to be effective for GI lesions that are refractory to glucocorticoid therapy ( 13 - 15 ). Several case series of remission induction for glucocorticoid-resistant GI lesions associated with IgAV have been reported ( Table ).…”