Intravenous amiodarone in the treatment of various arrhythmias following cardiac operations

Installé, Etienne; Schoevaerdts, Jean-Claude; Gadisseux, Ph.; Charles, S.; Trémouroux, J

doi:10.1016/s0022-5223(19)37640-8

Cited by 96 publications

(11 citation statements)

References 18 publications

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“…There were 22 clinical trials involving different pharmacologic agents and strategies in the treatment of post‐CABG AF, identified and summarized in Table 4 (11–32). Fourteen studies evaluated antiarrhythmic agents (11–23, 31) rather than the rate‐controlling agents; however, in six of these studies, an antiarrhythmic was compared with a rate‐controlling agent (11, 13, 16, 17, 19, 22). Five of these six trials compared the antiarrhythmic with digoxin, and the only endpoint evaluated was the time to conversion (11, 13, 16, 17, 19).…”

Section: Resultsmentioning

confidence: 99%

Assessment of new onset postcoronary artery bypass surgery atrial fibrillation: current practice pattern review and the development of treatment guidelines

2002

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Section: Resultsmentioning

confidence: 99%

Assessment of new onset postcoronary artery bypass surgery atrial fibrillation: current practice pattern review and the development of treatment guidelines

2002

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“…In these cases, systemic perfusion may be maintained during the initial bolus with additional pressors, and occasionally intra-aortic balloon counterpulsation. 23 If time permits, the negative inotropic effects of i.v. amiodarone are also mitigated by slowing the loading infusion.…”

Section: Drug Selection For Acute Management Of Unstable Vt and Vfmentioning

confidence: 99%

Perioperative cardiac arrhythmias

Thompson

Balser

2004

British Journal of Anaesthesia

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“…Oral amiodarone therapy needs frequent visits to the hospital and intense monitoring for side effects [9]. However, the onset of the antiarrhythmic effect of intravenous amiodarone is rapid [10,11].…”

Section: Introductionmentioning

confidence: 99%

Effect of Amiodarone in Prevention of Atrial Fibrillation Immediately After Release of Aortic Cross-Clamp

Sahu¹,

Samantaray

Behera³

2018

Asian J Pharm Clin Res

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Objective: The objective of this study is to determine the efficacy of a bolus dose of amiodarone administered by the way of cardiopulmonary bypass pump before releasing of aortic cross-clamp (ACC) in the prevention of atrial fibrillation.Methods: In this prospective study, 22 non-diabetic patients were randomly assigned in a double-blind fashion to either amiodarone or placebo group. In amiodarone group injection amiodarone 3 mg/kg in 10 ml normal saline (amiodarone group, Group A, n=10) and in control group (control group, Group P, n=12), the same volume of normal saline was administered 3 min before the release of ACC. Initial rhythm after the release of ACC was noted.Results: The major rhythm after the release of ACC was ventricular arrhythmia in control group (n=5, 40%), whereas in amiodarone group, it is normal sinus rhythm (n=7, 63%). Only the need of cardioversion/defibrillation and the amount of energy needed was less in the amiodarone group but not reached statistical significance level. There was a trend toward a higher ventricular rate in control group compared to amiodarone group, but it never reached statistical significance level (114±46 vs. 97±29, p=0.3). One patient in amiodarone group required temporary pacemaker for sustained atrioventricular block with heart rate of <50 beats/min and continued on temporary pacemaker for 48 h.

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Intravenous amiodarone in the treatment of various arrhythmias following cardiac operations

Cited by 96 publications

References 18 publications

Assessment of new onset postcoronary artery bypass surgery atrial fibrillation: current practice pattern review and the development of treatment guidelines

Assessment of new onset postcoronary artery bypass surgery atrial fibrillation: current practice pattern review and the development of treatment guidelines

Perioperative cardiac arrhythmias

Effect of Amiodarone in Prevention of Atrial Fibrillation Immediately After Release of Aortic Cross-Clamp

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