Intravascular synovial sarcoma

Abstract

A 52 year old woman had autoimmune hepatitis and an increased concentration of serum carbohydrate antigen 19-9 (CA19-9). The origin of the raised CA19-9 was studied using immunohistochemistry. Liver biopsy section showed chronic active hepatitis with large numbers of proliferated bile ductules. Immunohistochemical analysis revealed that the proliferated bile ductule cells were positive for proliferating cell nuclear antigen (PCNA) and for CA19-9. It is speculated that the raised serum CA19-9 concentration was derived from proliferated bile ductule cells and these cells, which are positive for PCNA, may be able to produce high concentrations of CA19-9. (J Clin Pathol 1998;51:167-169)

Synovial sarcoma in older patients: clinicopathological analysis of 32 cases with emphasis on unusual histological features

“…Surgical treatment consisted of marginal excision (10 ⁄ 32) or wide excision (21 ⁄ 32); one patient underwent only surgical debulking due to difficulty in resection given the tumour location and size (100 mm, neck). Six patients received postoperative radiation therapy (patients 8,10,13,17,25,29). Patient 10 received both preoperative and postoperative radiation.…”

“…The vast majority arise in the extremities (85–90%) but a variety of unusual sites have also been documented. These locations include the head and neck region, 8,9 abdominal wall, 10 genitourinary tract, 11,12 chest wall/intrathoracic, 13–15 intraosseous, 16 intravascular, 17 intraneural 18 and intracranial 19 sites.…”

Intraneural synovial sarcoma: two cases

“…Less than 20% of cases of SS occur away from the extremities, such as in the head and neck, the chest or the abdominal wall. 1 Rare cases of SS have been identified in organs without any apparent relationship to synovial structures, such as the pleura, 2-4 heart, 5-8 kidney, 9,10 prostate, 11 intravascular spaces, 12,13 penis, 14,15 gastrointestinal tract, 16,17 parotid gland 18 and vulva. 19 To the best of our knowledge, there have only been five cases of intraneural synovial sarcoma (INSS) reported in the literature.…”

Primary intravascular synovial sarcoma: A disease of young adult women? report of a case diagnosed by aspiration biopsy and review of the literature

“…IVSS is an exceedingly rare tumor with the current case being the fifth reported in the English literature. [4][5][6][7] The clinical and histologic features are summarized in Table I. All five patients with IVSS were women aged 34, 31, 34, 32, and 56 yr.…”

“…2,3 Primary intravascular synovial sarcoma (IVSS) is exceedingly rare and there are only four well-documented cases reported in the English literature. [4][5][6][7] As fine-needle aspiration biopsy (FNAB) is increasingly used in the initial evaluation of a mass lesion, this rare entity may represent a diagnostic challenge for cytopathologists. Here, we report an additional case of IVSS in a 32-yr-old woman evaluated initially by CT-guided FNAB.…”