Intravascular Myopericytoma in the Heel

Abstract

Intravascular myopericytoma (IVMP), regarded as a variant of myopericytoma, is a rare tumor. Very few cases have been described, none in the foot.The first case of IVMP located in the heel of the foot is described in this article. A literature review is reported of all cases of IVMP published in the English literature.A 48-year-old man possessed an IVMP on the heel of the right foot. The physical examination and histopathological and ultrasound studies are described. The literature review yielded 5 cases of IVMP, 2 of which were in the thigh and 1 each in the oral mucosa, the periorbital region, and the leg.The possibility that these lesions may be malignant suggests that the histopathological study of vascular tumors should include immunohistochemical tests.

Myopericytoma occurrence in the liver and stomach space: imaging performance

“…The size was 0.5 × 0.5–4.1 × 5.3 cm 2 [ 5 , 12 – 16 ]. Ultrasound examination showed the lesions were usually homogeneous hypoechoic with clear boundaries [ 17 – 19 ] and with obvious blood flow [ 17 , 18 ]. Conventional CT examinations found that the lesions were usually isodense or hypodense, homogeneous or heterogeneous, occasionally calcified, and clearly bounded [ 14 , 18 , 20 – 24 ].…”

Foot soft tissue myopericytoma: Case-report and review

“…Agusti et al describe another case of myopericitoma on the foot plantar region and explains the likely origin from a cutaneous vascular malformation [26] . Another area where myopericitoma may develop is the heel [27] . Finally, Squillaci et al described another myopericitoma of foot soft tissue concluding that clinico-pathological features are similar to those previously reported in the literature [28] ( Table 1 ).…”

“… Diffusely positive for SMA and h-caldesmon; negative for desmin and CD34. Intravascular Myopericytoma in the Heel: Case Report and Literature Review [27] 1 1M 48 years old Heel of the right foot 1,5 × 0,4 cm Lesion in the subcutaneous tissue; a venous-type vascular structure, was partially occupied by a proliferation of spindle-shaped cells Positive for SMA and caldesmon, but not CD34 antobody, desmin, factor VIII, epithelial membrane antigen, or cytokeratins. Myopericytoma-type perivascular myoma located in the soft tissue of the foot.…”

Diagnostic dilemma in soft tissue swelling over finger

“…The lesion is generally located in the dermis and subcutaneous tissue and has a predilection for distal extremities, but it may be found in any part of the body [2]. It is composed of oval to spindle-shaped myoid-appearing cells with a strong tendency towards concentric perivascular growth [2,3]. An intravascular myopericytoma (IVMP) is a distinct, histological variant [1] and has been rarely documented.…”

“…While most MPs are painless, the intravascular subtype tends to have a painful course which can be attributed to the thrombus associated with the lesion [4,5]. The tumor shares the morphological characteristics with many entities that can be intravascular - angioleiomyoma, glomus tumor, perivascular myoma, hemangiopericytoma, myofibroma, myofibromatosis, papillary endothelial hyperplasia and pyogenic granuloma [3,4,6]. The distinctive feature of intravascular myopericytoma from other perivascular myoid tumors is that it shows a biphasic pattern: whorled nodules with bundles of mature eosinophilic cells, and immature small mesenchymal cells associated with numerous thin-walled hemangio-pericytoma like vessles [4,7,8].…”