Intratympanic membrane cholesteatoma: a rare incidental finding

Reddy, C. Ekambar Eshwara; Goodyear, P; Ghosh, Samit; Lesser, T. H. J.

doi:10.1007/s00405-006-0156-1

Cited by 18 publications

(27 citation statements)

References 14 publications

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“…Intratympanic membrane cholesteatoma without any adverse events, such as our two cases, can be considered of congenital origin [2,5,7,10]. However, the true cause of this lesion is still unknown because the pathogenesis of congenital cholesteatoma in the middle ear is unclear.…”

Section: Discussionmentioning

confidence: 68%

“…Intratympanic membrane cholesteatoma without any adverse events in the middle ear or on the tympanic membrane has been detected as an incidental finding on routine examination of the ear [7]. Therefore, not only otolaryngologists but also pediatricians and primary care physicians should routinely perform otoscopy on every child in order to screen for this lesion.…”

Section: Discussionmentioning

confidence: 96%

“…Moreover, only a few reports of intratympanic membrane cholesteatoma without a history of otitis media or any other adverse events are found in the literature [2,5,7,10].…”

Section: Discussionmentioning

confidence: 99%

“…Some cases of this disease have had episodes of otitis media [4,6,[8][9][10], but cholesteatoma of the tympanic membrane without any other adverse events is extremely rare and this lesion is considered to be of congenital origin [7]. Reddy et al [7] opined that primary care physicians and pediatricians should routinely perform otoscopy on every child because most cases are found only by chance. Cholesteatoma should be removed by excision of the involved part of the tympanic membrane or enucleation before it begins to progress.…”

Section: Introductionmentioning

confidence: 98%

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Two Cases of Congenital Cholesteatoma of the Tympanic Membrane

Matsuda

Satake

Takahashi

et al. 2011

Indian J Otolaryngol Head Neck Surg

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Congenital cholesteatoma of the tympanic membrane is rare, and lesions without a history of otitis media or any other adverse events involving the tympanic membrane are extremely rare. We report two cases of this lesion; one was a 3-year-old girl who underwent removal of a cholesteatoma using retroauricular approach and a partial myringoplasty with an underlay technique, and the other was a 2-year-old girl in whom a cholesteatoma was enucleated without grafting. This disease is thought to be of embryonic origin.

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Section: Discussionmentioning

confidence: 68%

Section: Discussionmentioning

confidence: 96%

“…Moreover, only a few reports of intratympanic membrane cholesteatoma without a history of otitis media or any other adverse events are found in the literature [2,5,7,10].…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 98%

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Two Cases of Congenital Cholesteatoma of the Tympanic Membrane

Matsuda

Satake

Takahashi

et al. 2011

Indian J Otolaryngol Head Neck Surg

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“…Table 2 summarizes the data found in the English literature [5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24] .…”

Section: Discussionmentioning

confidence: 99%

Congenital Intratympanic Cholesteatoma in an Adult Patient: A Case Report and Review of the Literature

Pedruzzi

Mion²,

Comacchio³

2016

Int Adv Otol

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Congenital cholesteatoma within the tympanic membrane is an uncommon entity, with only few cases being documented. The aetiopathogenesis of this lesion is still unknown; however, when cholesteatoma develops in subjects without any history of previous ear inflammation, as in the case we report here, an embryologic origin is deeply suspected. An acquired origin is hypothesized in patients with a previous history of an inflammatory process of the external or middle ear because of the proliferation of the basal cell layer of the tympanic membrane epithelium. We report a rare case of congenital cholesteatoma of the tympanic membrane in an adult patient and review the literature KEYWORDS: Congenital intratympanic cholesteatoma, intratympanic cholesteatoma, congenital cholesteatoma of the tympanic membrane, cholesteatoma of the tympanic membrane Barbara Pedruzzi, Marta Mion, Francesco ComacchioDepartment of Otolaryngology, Azienda Ospedaliera di Padova, Padova, Italy Case ReportIn 1936, Teed [3] cited the first five cases of ITMC to support the theory of a congenital origin of cholesteatomas. From the English literature, he cited the first case reported by Hinton in 1863 [4] and one other case.We identified a list of potential citations for inclusion in this review, following which the titles and abstracts on this list were screened by two independent reviewers.All the retrieved full-texts were included in the review by consensus of all the authors ( Figure 5).As a quality assessment strategy, the included studies were methodologically appraised according to the National Institute for Health and Clinical Excellence's levels of evidence (Table 1): all the studies could be categorized as evidence level 3.We analyzed the data from these cases, including our own case, to study their demographic details, and clinical features and management, for a total of 42 patients and 20 articles, including our own research (Table 2). Table 2 summarizes the data found in the English literature [5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24] . 120J Int Adv Otol 2016; 12(1): 119-24 The age range was 5 months to 57 years, with 27 (64.3%) cases involving patients less than 4 years of age, out of which seven (16.7%) were 1-year old or less. There was a history of one or more episodes of otitis media (n=14) when ITMC was noticed on otoscopy. The lesion was first noted by pediatricians (n=14), by general practitioners (n=4), or by otolaryngologists (n=16). In three cases, the analyses were conducted post-mortem during autoptic exams [9] . This highlights the need for routine otoscopy by primary care physicians to detect abnormalities and make an early referral to otolaryngologists. ITMC should always be considered in the differential diagnosis of white lesions in TM. Otomicroscopy can help differentiate ITMC from tympanosclerosis. Only in one case had the lesion occupied the whole TM, while the umbo was involved in nine patients; this region is the most depressed part of TM, where the manubrium of the malleus is fir...

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Pathologie de l’oreille

Wassef

2009

Annales de Pathologie

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Intratympanic membrane cholesteatoma: a rare incidental finding

Abstract: Intratympanic membrane cholesteatoma, occurring in the absence of trauma or surgery to the ear, is rare with less than 20 cases reported in the literature. We report a rare incidental finding of intratympanic membrane cholesteatoma in a 12-month-old girl and review the literature.

Cited by 18 publications

References 14 publications

Two Cases of Congenital Cholesteatoma of the Tympanic Membrane

Two Cases of Congenital Cholesteatoma of the Tympanic Membrane

Congenital Intratympanic Cholesteatoma in an Adult Patient: A Case Report and Review of the Literature

Pathologie de l’oreille

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