Intraperitoneal insemination in the treatment of male and unexplained infertility

Crosignani, P.G.; Ragni, G.; Finzi, Gcl; Lauretis, L. De; Olivares,; Perotti, L.

doi:10.1016/0020-7292(92)90983-p

Cited by 11 publications

(11 citation statements)

References 19 publications

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“…The aim of this study was to compare seminal parameters of sperm prepared by a direct swimup technique and sperm additionally incubated in TYB. In addition, TYB-incubated spermatozoa were inseminated intraperitoneally into 11 women who had attempted the same procedure three times without success (Crosignani et al, 1991).…”

Section: Introductionmentioning

confidence: 99%

Enhanced quality of capacitated spermatozoa from oligoasthenozoospermic men after incubation in test yolk medium

Ragni

Finzi²,

Caccamo³

et al. 2009

Andrologia

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To improve artificially the quality of poor sperm samples to be used in assisted procreation procedures, Test Yolk Buffer (TYB) incubation effect was investigated. After adding the TYB procedure to the standard swim-up technique, a significant ( P < 0.00 1) increase in spermatozoa velocity was observed, while the other seminal parameters were not affected.Three of 11 couples who had not had success after three intraperitoneal inseminations (IPI) with sperm prepared by the usual swim-up technique obtained pregnancies after IPI with TYBincubated spermatozoa.These preliminary results suggest that TYB incubation for capacitated spermatozoa be employed in the assisted procreation strategies applied for male infertility.

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Section: Introductionmentioning

confidence: 99%

Enhanced quality of capacitated spermatozoa from oligoasthenozoospermic men after incubation in test yolk medium

Ragni

Finzi²,

Caccamo³

et al. 2009

Andrologia

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“…The reasons for the improved pregnancy rate with controlled superovulation are: development of an increased number of oocytes, improved function of corpus luteum, improved quality of cervical mucus or improved receptivity of the endometrium to the embryo (5,6). Furthermore, an increase in the content of local estrogen may favor the capacitation of spermatozoa (7). Although couples whose unexplained infertility has been treated with only expectant management may have fairly good pregnancy rates, infertility treatment of any kind improves their chances of achieving pregnancy (8)(9)(10).…”

mentioning

confidence: 99%

Superovulation combined with insemination or timed intercourse in the treatment of couples with unexplained infertility and minimal endometriosis

Isaksson

Tiitinen

1997

Acta Obstet Gynecol Scand

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“…More recently, direct intraperitoneal insemination with washed sperm (DIPI), first proposed by Manhes & Hermabkssiere (1985), has been regarded as a valuable therapeutic tool in cases of unexplained, cervical or male-related infertility (Forrler et al, 1986;Guastella & Cimino, 1986;Studd et al, 1987;Cohen at al., 1988;Crosignani et al, 1991).…”

Section: Introductionmentioning

confidence: 99%

Influence of peritoneal fluid from spontaneous and stimulated cycles on sperm motility in vitro

et al. 2009

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Peritoneal fluids (PFs) from spontaneous ( n = 14) and gonadotrophin-stimulated cycles (n = 20) were obtained during diagnostic laparoscopy and gamete intrafallopian transfer (GIFT) procedures, respectively. The effects of these fluids on the linear component of sperm motility and on the percentage of motile spermatozoa were studied in uitra by objective motility assessments and compared to a control medium (B,-Mhkzo).Overall, the two types of PFs were found to have rather similar effects on the motility parameters studied. However, the fluids from hormonally-stimulated cycles sustained motility better (i.e., sperm velocity and percentage of motile sperm) and in a rather constant manner as a function of time (narrower range distributions of the motility measurements). Furthermore, it was observed that under identical experimental conditions motility measurements depended not only on the type of PF used but also on the sperm sample.These results suggest that assisted reproduction procedures in which PF is the medium where the gametes eventually meet and interact, such as direct peritoneal insemination (DIPI) or peritoneal oocyte and sperm transfer (POST), could have different success rates if performed in spontaneous rather than in stimulated cycles. At the same time, our results may help to explain why different pregnancy rates were reported in different studies using D I P or POST.

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Intraperitoneal insemination in the treatment of male and unexplained infertility

Cited by 11 publications

References 19 publications

Enhanced quality of capacitated spermatozoa from oligoasthenozoospermic men after incubation in test yolk medium

Enhanced quality of capacitated spermatozoa from oligoasthenozoospermic men after incubation in test yolk medium

Superovulation combined with insemination or timed intercourse in the treatment of couples with unexplained infertility and minimal endometriosis

Influence of peritoneal fluid from spontaneous and stimulated cycles on sperm motility in vitro

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