Intraosseous gout mimicking giant cell tumor of the patella

Chiu, Michael K.; Lewis, Nicholas

doi:10.1007/s00256-020-03422-y

Cited by 4 publications

(3 citation statements)

References 10 publications

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“…The histological findings in PGDD and gout are similar and difficult to differentiate between them using HE staining. There are reports of cases of intraosseous tophaceous gout with normal serum uric acid levels, leading to confusion 15,16 . As GHA staining can detect the ester bonds of phosphoglycerides under the light microscope by variants of the hydroxamic acid reaction, this staining is considered a useful tool to distinguish PGDD from other crystal forming conditions 17,18 .…”

Section: Discussionmentioning

confidence: 99%

Phosphoglyceride Crystal Deposition Disease of the Scapula

Hori¹,

Nagano²,

Miyazaki

et al. 2023

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Case:A 76-year-old woman presented with a 2-month history of right shoulder pain with no apparent cause. Radiography revealed an ill-defined osteolytic lesion in the right scapular spine with a pathological fracture. Malignant bone tumor was suspected, and a biopsy was performed. Pathological examination with gold hydroxamic acid staining revealed phosphoglyceride crystal deposition. Lesion curettage was performed, and her symptoms improved. No recurrence was observed at the 3-year postoperative follow-up.Conclusion:Phosphoglyceride crystal deposition in the bone is an extremely rare disease. The gold hydroxamic acid staining method might be useful for the diagnosis of this condition.

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Section: Discussionmentioning

confidence: 99%

Phosphoglyceride Crystal Deposition Disease of the Scapula

Hori¹,

Nagano²,

Miyazaki

et al. 2023

JBJS Case Connector

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“…Gout classically presents as sudden monoarthritic pain, most common at the first metatarsophalangeal joint. It has been hypothesized that the predilection for gout at the first metatarsophalangeal joint is due to decreased monosodium urate solubility at the surrounding lower temperature of the foot [25]. Similarly, the superficial location of the patella may also result in a lower temperature that increases the likelihood of gouty tophus formation [25].…”

Section: Goutmentioning

confidence: 99%

“…Patellar gout has also been associated with history of trauma, bipartite patella, and additional inflammatory disease [25]. Although patellar gout may be seen at both the quadriceps and patellar tendon attachments, the superolateral quadriceps attachment is more common [25].…”

Section: Goutmentioning

confidence: 99%

Lucent Patellar Lesions: A Pictorial Review

Chow

Levine

et al. 2022

Radiology Case

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A radiographically lucent patellar lesion may represent a variety of etiologies, ranging from more commonly seen degenerative, metabolic, infectious, developmental, posttraumatic, postoperative causes to rarer benign and malignant neoplasms. Clinical symptoms, surgical history, laboratory values, and radiographic features may help narrow the differential. In addition, radiographic features such as circumscribed borders and sharply delineated margins favor benign lesions while ill-defined margins suggest malignant etiologies. This case series illustrates the imaging findings and explores relevant clinical findings in a variety of interesting lucent patellar lesions.

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