Intraoral fluoride levels after use of conventional and high-fluoride dentifrices

Pessan, Juliano Pelim; Conceição, Juliana Mendonça da; Grizzo, Larissa Tercília; Székely, Melinda; Fazakas, Zita; Buzalaf, Marília Afonso Rabelo

doi:10.1007/s00784-015-1426-3

Cited by 17 publications

(26 citation statements)

References 21 publications

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“…group that did not. These findings are in line with studies by Bayrak, Okte and Fidanci 1 assessing primary and permanent dentitions and Pearce et al 23 assessing permanent dentition. However, they do not corroborate the results obtained by Gaugler and Bruton 6 (1982) and Dos Santos et al 17 Compared to the study of Dos Santos et al 17 the caries diagnosis criteria used in their study did not include ECL.…”

Section: Discussionsupporting

confidence: 92%

<p>Plaque Fluoride Levels as a Predictor of Caries Development in Early Childhood with High Sugar Exposure – A Preliminary Study</p>

Rizzardi

Rodrigues

Steiner‐Oliveira

et al. 2020

CCIDE

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Objective: This longitudinal study aimed to investigate if the plaque fluoride (PF) concentration can predict the early childhood caries onset. Design: As part of a larger study, 188 preschoolers were clinically evaluated for early childhood caries diagnosis, at baseline and after 1-year follow-up. After that, the final sample comprised: 1. children who had already caries at baseline (decayed, missing or filled surfaces, as well as white chalky white spot lesions adjacent to gingival margins) and developed at least one more cavitation after one year (n=16), and 2. children who never had or developed any caries lesions, including active white spots lesions (n=15). Before the clinical examinations, dental plaque was collected. PF concentration was determined with an ion-specific electrode. A chart was used to estimate the mean daily sugar exposure. The results were statistically analyzed by Spearman correlation and logistic regression analyses (α=0.05). Results: After one year, a positive significant correlation between caries development and liquid sucrose, total sugar and total sucrose consumption increments was found (p<0.05). Moreover, the solid sugar, solid sucrose and total sugar exposure at baseline were positively correlated with the presence of dental plaque at follow-up (p<0.05). To top it all, children with PF concentrations ≤0.1 μg/mg at baseline were 10 times more likely to develop caries. Conclusion: In conclusion, this study demonstrated for the first time in vivo that low PF concentration is a predictor of caries development in primary teeth.

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Section: Discussionsupporting

confidence: 92%

<p>Plaque Fluoride Levels as a Predictor of Caries Development in Early Childhood with High Sugar Exposure – A Preliminary Study</p>

Rizzardi

Rodrigues

Steiner‐Oliveira

et al. 2020

CCIDE

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“…High‐fluoride dentifrice is able to significantly increase intraoral F levels, and it has been used to control caries in root dentine. This substrate is more susceptible to demineralisation than enamel and requires higher concentrations of fluoride to control de‐remineralisation processes .…”

Section: Introductionmentioning

confidence: 99%

“…1 Concerning the approaches of fluoride use, fluoridated dentifrice is the most rational, 10 because it associates the mechanical disorganisation of biofilm with the preventive and therapeutic interference of F, 11,12 due tothe maintenance of F levels in biofilm [13][14][15] for up to 10 hours or more after brushing. 14 High-fluoride dentifrice is able to significantly increase intraoral F levels, [16][17][18] and it has been used to control caries in root dentine. This substrate is more susceptible to demineralisation than enamel and requires higher concentrations of fluoride to control de-remineralisation processes.…”

mentioning

confidence: 99%

Root dentine demineralisation according to frequency of sucrose exposure using high‐fluoride dentifrice

et al. 2019

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Objective To evaluate root dentine demineralisation, biomass and loosely bound fluoride (CaF2) concentration according to different frequencies of sucrose exposure using a high‐fluoride dentifrice. Background Although high‐fluoride dentifrice has been recommended to arrest root dentine lesions, it is not clear whether it can protect dentine from increased frequencies of sucrose exposure. Methods An in situ, crossover, split‐mouth study was conducted in 3 phases with 7 days each, in which 10 volunteers used a palatal device containing 4 bovine root dentine slabs (2 on each side) with predetermined initial hardness. Cariogenic challenge consisted in dripping a 20% sucrose solution 0 (control), 2, 4, 6, 8 or 10 times/d in each block. Volunteers used high‐fluoride dentifrice (NaF, 5000 µg F/g) 3 times/d. After each phase, final hardness was measured and the percentage of surface hardness loss (%SHL) calculated. Also, biomass and CaF2 concentration on dentine were determined. The data were processed and analysed by ANOVA and Tukey test with significance level set at 5%. The relationship between the variables was analysed by linear regression and Pearson correlation (r). Results %SHL and biomass were significantly greater than control for sucrose frequencies higher than 6 times/d (P < 0.001), while CaF2 concentration decreased from sucrose frequency higher than 2 times/d (P < 0.001). Regression analysis data showed a significant linear fit between sucrose exposure frequency and the studied variables with a strong correlation (r) for %SHL and CaF2 and moderate for biomass (P < 0.05). Conclusion High‐fluoride dentifrice is able to reduce root dentine demineralisation if sucrose consumption is not higher than 6 times/d.

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“…Entre los elementos de aplicación tópica están las cremas dentales con flúor, consideradas un medio eficaz en la remoción mecánica de placa bacteriana y una forma de mantener las concentraciones de flúor disponibles en la saliva, en el biofilme y en la estructura dentaria que evitan los procesos de desmineralización. Además de ser la forma más usada y aceptada por la población mundial para el control de la caries dental y la enfermedad periodontal del esmalte [2].…”

Section: Introductionunclassified

Concentración de flúor en cremas dentales y enjuagues bucales para niños vendidos en la ciudad de Bogotá, Colombia

et al. 2016

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Introducción:el uso de flúor ayuda en el control de la caries dental; las cremas dentales y los enjuagues bucales constituyen los medios de aplicación más usados por la población. Objetivo: determinar las concentraciones de flúor en las cremas dentales y enjuagues bucales para niños, vendidos en los supermercados de la ciudad de Bogotá y verificar si estos valores estaban consistentes con los informados por los fabricantes. Materiales y Métodos: fueron encontradas 17 cremas dentales y 4 enjuagues bucales. En todas las cremas dentales fue evaluado el flúor total (FT) y flúor iónico (FI); en las que contenían Monofluorofosfato de Sodio adicionalmente se evaluó el flúor soluble total (FST). En los enjuagues bucales se evaluó flúor iónico (FI). Para los análisis fue usado un electrodo específico de flúor acoplado a un analizador de iones, calibrado previamente con padrones de flúor después de adicionar TISAB II como solución tampón. Se realizó un análisis estadístico descriptivo de los datos. Resultados: el 18% de las cremas dentales presento valores entre 12,46 a 13,93% por debajo del valor esperado para el FT. Para el FI una presento valores del 77% menos de lo esperado, que fue la misma con valores en FST del 48,7% menor a lo esperado. Uno de los enjuagues bucales obtuvo un valor de FI 7% mayor a lo esperado. Conclusión: la mayoría de las cremas dentales y enjuagues bucales analizados presentan valores de FT y FI de acuerdo a la información presentada por los fabricantes. Sin embargo, se observó inconsistencia en la concentración de flúor en algunos productos que puede afectar su efecto anticaries.

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Intraoral fluoride levels after use of conventional and high-fluoride dentifrices

Abstract: A dentifrice with high fluoride concentration could be regarded as a useful therapy of F delivery for high caries-risk patients, since intraoral F levels were sustained throughout most of the day after using this formulation.

Cited by 17 publications

References 21 publications

<p>Plaque Fluoride Levels as a Predictor of Caries Development in Early Childhood with High Sugar Exposure – A Preliminary Study</p>

<p>Plaque Fluoride Levels as a Predictor of Caries Development in Early Childhood with High Sugar Exposure – A Preliminary Study</p>

Root dentine demineralisation according to frequency of sucrose exposure using high‐fluoride dentifrice

Concentración de flúor en cremas dentales y enjuagues bucales para niños vendidos en la ciudad de Bogotá, Colombia

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