Root dentine demineralisation according to frequency of sucrose exposure using high‐fluoride dentifrice

Abstract

Objective To evaluate root dentine demineralisation, biomass and loosely bound fluoride (CaF2) concentration according to different frequencies of sucrose exposure using a high‐fluoride dentifrice. Background Although high‐fluoride dentifrice has been recommended to arrest root dentine lesions, it is not clear whether it can protect dentine from increased frequencies of sucrose exposure. Methods An in situ, crossover, split‐mouth study was conducted in 3 phases with 7 days each, in which 10 volunteers used a palatal device containing 4 bovine root dentine slabs (2 on each side) with predetermined initial hardness. Cariogenic challenge consisted in dripping a 20% sucrose solution 0 (control), 2, 4, 6, 8 or 10 times/d in each block. Volunteers used high‐fluoride dentifrice (NaF, 5000 µg F/g) 3 times/d. After each phase, final hardness was measured and the percentage of surface hardness loss (%SHL) calculated. Also, biomass and CaF2 concentration on dentine were determined. The data were processed and analysed by ANOVA and Tukey test with significance level set at 5%. The relationship between the variables was analysed by linear regression and Pearson correlation (r). Results %SHL and biomass were significantly greater than control for sucrose frequencies higher than 6 times/d (P < 0.001), while CaF2 concentration decreased from sucrose frequency higher than 2 times/d (P < 0.001). Regression analysis data showed a significant linear fit between sucrose exposure frequency and the studied variables with a strong correlation (r) for %SHL and CaF2 and moderate for biomass (P < 0.05). Conclusion High‐fluoride dentifrice is able to reduce root dentine demineralisation if sucrose consumption is not higher than 6 times/d.

<p>Development of an Experimental Dentifrice with Hydroxyapatite Nanoparticles and High Fluoride Concentration to Manage Root Dentin Demineralization</p>

“…Several studies associate the increase of F − concentration in dentifrices with the effectiveness in the dental demineralization. [33][34][35] F − acts by incorporating the ion into hydroxyapatite, which results in the formation of fluorapatite during the demineralization and remineralization process. The critical pH, which is the pH at which tooth dissolution begins to occur, is lower for fluorapatite.…”

Dose-Response Effect of Fluoride Dentifrices on De-/Remineralization of Root Dentine in situ

“…The short in situ period was chosen based on other studies that used the same period to evaluate dentine demineralization [Vale et al, 2007[Vale et al, , 2011Rolim et al, 2019]. Furthermore, in an in situ study with 14 days of duration, the authors were not able to properly evaluate the SH of dentine because the limits of the indentations made were not clearly visualized to allow an accurate determination [Fernández et al, 2017].…”