“…Results at pre, post, 2, 4, and 24 hours later: for sumatriptan 7.3, 4.6, 3.54, 2.75, and 2.92; for intraoral chilling 7.33, 3.5, 2.33, 2.04, and 1.1; for tongue chilling 7.2, 6.0, 5.6, 5.8, and 4.36. 15 Topical Ketoprofen Headache Prevention Study.-Headache burden, which equals total monthly headache hours × average severity (0 to 10 scale) decreased from 454.8 (30-day baseline) to 86.5 P < .001 during the 30-day treatment phase. Analgesic and headache medication intake were significantly reduced from baseline during the treatment phase, with minimal side effects.…”