Intraoral adenoid cystic carcinoma: Prognostic factors and outcome

Agarwal, Jai Prakash; Jain, Sandeep; Gupta, Tejpal; Tiwari, Mayank; Laskar, Siddhartha; Dinshaw, Ketayun A.; Chaturvedi, Pankaj; D’Cruz, Anil; Shrivastava, SK

doi:10.1016/j.oraloncology.2008.01.004

Cited by 46 publications

(42 citation statements)

References 21 publications

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“…MECs can range from a low grade tumor to a high-grade carcinoma. Furthermore ADCC is a high grade neoplasm with various histopathological features including solid, tubular and cribriform patterns (Agarwal et al, 2008). These histopathological isoforms in a specific tumor affects the grading and clinical course of the tumor.…”

Section: Discussionmentioning

confidence: 99%

MCM3 as a Novel Diagnostic Marker in Benign and Malignant Salivary Gland Tumors

Jaafari‐Ashkavandi¹,

Najvani²,

Tadbir³

et al. 2013

Asian Pacific Journal of Cancer Prevention

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Section: Discussionmentioning

confidence: 99%

MCM3 as a Novel Diagnostic Marker in Benign and Malignant Salivary Gland Tumors

Jaafari‐Ashkavandi¹,

Najvani²,

Tadbir³

et al. 2013

Asian Pacific Journal of Cancer Prevention

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“…According to the literature [1,6] and in this report adenoid cystic carcinoma occurs in most cases in the fourth and sixth decade of life and is slightly more common in women than in men. Salivary gland tumors rarely develop within maxillary and mandibular bony tissue [9].…”

Section: Discussionmentioning

confidence: 61%

“…Kim et al [13], have also reported frequent occurrence of ACC in minor salivary glands of the nose and paranasal sinuses. Surgery was the prime treatment to Adenoid cystic carcinoma like in the others studies [1,5,6,8,12]. However, it is often diffi cult to obtain a complete resection because of vascular invasion and perineural infi ltration [8].…”

Section: Discussionmentioning

confidence: 99%

“…Due to lack of highquality evidence, optimal treatment continues to evolve over time [1]. This rare epithelioid head and neck tumor accounting for about 7.5% of all salivary gland malignancies [2] and in the oral cavity this entity comprises only 6.3-10.2% of all minor salivary gland tumors [3].…”

Section: Introductionmentioning

confidence: 99%

“…Surgical resection with clear margins is currently considered as the standard of care for a vast majority of patients with minor salivary gland tumors including ACCs [1,5].…”

Section: Introductionmentioning

confidence: 99%

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Adenoid Cystic Carcinoma of the Maxilla, CT Follow-Up: A Case Report

Caputo¹,

Filho²,

Costa³

et al. 2017

Int J Radiol Radiat Oncol

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Background: Intraoral adenoid cystic carcinoma is an uncommon pathology with a variable clinical course, it develops as a slow growing swelling characterized by wide local infi ltration. Most patients are in their fourth and sixth decades of life, and females are slightly more affected than males.Case report: An 46-years-old woman was seen at University Hospital of Cuiabá with strong pain in the upper edge of the right side region. Patient reported being subjected to tooth extraction in the area where the pain was equivalent to 4 years, and in intraoral examination revealed an increase in volume of the region of the right side palate. The patient was submitted to the radical surgery promoting the removal of the lesion in the areas of the right maxilla, maxillary sinus and fl oor of the right orbit. The diagnosis was adenoid cystic carcinoma and after one year of follow-up the patient showed no presence of recurrences.

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Multicenter study of carbon‐ion radiation therapy for nonsquamous cell carcinomas of the oral cavity

et al. 2019

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Background The aim of this study was to evaluate the efficacy and safety of carbon‐ion radiation therapy for nonsquamous cell carcinomas of the oral cavity in a multicenter study. Methods Retrospective analysis of the clinicopathological features and outcomes of 76 patients with oral nonsquamous cell carcinomas with N0‐1 M0 status and were treated with carbon‐ion radiation therapy at four institutions in Japan between November 2003 and December 2014 was performed. Results Salivary gland carcinoma, mucosal melanoma, and three other carcinomas were found in 46, 27, and 3 patients, respectively. T1‐3, T4a, and T4b disease was diagnosed in 27, 18, and 31 patients, respectively. Median follow‐up period was 31.1 months (range, 3‐118 months). Three‐year local control, progression‐free survival, and overall survival of all patients were 86.8%, 63.1%, and 78.4%, respectively. Multivariate analysis showed T classification (T4) to be a significant independent poor prognostic factor for local control. Acute grade 3 mucositis was observed in 38 patients. Grades 3 and 4 late morbidities were observed in 9 and 4 patients, respectively. No grade 5 late toxicity was observed. Conclusions Oral nonsquamous cell carcinomas could be treated effectively, with acceptable toxicity, by carbon‐ion radiation therapy.

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Intraoral adenoid cystic carcinoma: Prognostic factors and outcome

Cited by 46 publications

References 21 publications

MCM3 as a Novel Diagnostic Marker in Benign and Malignant Salivary Gland Tumors

MCM3 as a Novel Diagnostic Marker in Benign and Malignant Salivary Gland Tumors

Adenoid Cystic Carcinoma of the Maxilla, CT Follow-Up: A Case Report

Multicenter study of carbon‐ion radiation therapy for nonsquamous cell carcinomas of the oral cavity

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