Intraocular T-cell Lymphoma due to Mycosis Fungoides and Response to Intravitreal Methotrexate

Reddy, Rahul; Kim, Stephen Jae

doi:10.3109/09273948.2011.563896

Cited by 12 publications

(6 citation statements)

References 8 publications

(6 reference statements)

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“…T-cell IOL in the past 19,22,25 and two SRD cases were recently described on T-cell IOL. 29,30 A low rate of SRD was previously reported in B-cell lymphoma (10-28%).…”

Section: Discussionmentioning

confidence: 95%

Intraocular T-cell Lymphoma: Clinical Presentation, Diagnosis, Treatment, and Outcome

Chaput

Amer

Baglivo

et al. 2016

Ocular Immunology and Inflammation

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“…T-cell IOL in the past 19,22,25 and two SRD cases were recently described on T-cell IOL. 29,30 A low rate of SRD was previously reported in B-cell lymphoma (10-28%).…”

Section: Discussionmentioning

confidence: 95%

Intraocular T-cell Lymphoma: Clinical Presentation, Diagnosis, Treatment, and Outcome

Chaput

Amer

Baglivo

et al. 2016

Ocular Immunology and Inflammation

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“…Infiltrative conjunctival envelopment can be managed with radiotherapy and topical corticosteroids [16]. Choroid, retina, vitreous or optic disc infiltrations are associated guarded prognoses and may be treated with intravitreal methotrexate or other systemic chemotherapy drugs (5-fluorouracil, leucovorin) and/or localized radiation [25].…”

Section: Discussionmentioning

confidence: 99%

Mycosis Fungoides: Analysis of Ophthalmologic Findings in a Series of Cases

Colossi

Mondadori

Barreto

et al. 2019

Case Reports in Dermatological Medicine

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Background Ophthalmic findings in mycosis fungoides (MF) can be highly variable. It seems that the prevalence of ophthalmic findings could be much more common than previously assumed. Objective To present case series examined in the last 12 months, together with a literature review. Methods Symptomatic patients with biopsy-proven mycosis fungoides were examined ophthalmologically in a 12-month period. The medical records of affected patients were reviewed. Results Eight patients were examined. Of these, 75% were male, all were Caucasian, and average age was 58.2 years. Blepharitis (50.0%), thickened eyelids (37.5%), and flaking (25.0%) were the most prevalent findings. Conclusion Incidence of MF affecting the eyes and surrounding structures may be greater than estimated. Early case management offers means to reduce difficulties experienced with later diagnosis. Regular monitoring by an ophthalmologist is justified, including that of asymptomatic cases.

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“…9 Isolated vitritis, panuveitis, chorioretinal lesions, and optic nerve infiltration have been described with MF previously. [10][11][12][13][14] Intraocular disease is usually managed with radiotherapy or intravitreal injections of methotrexate. Vitreous involvement in the patient in case 2 was successfully treated with intravitreal methotrexate.…”

Section: Discussionmentioning

confidence: 99%

Clinical Variability of Ocular Involvement in Mycosis Fungoides

Jusufbegovic

Char

2015

JAMA Ophthalmol

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Intraocular T-cell Lymphoma due to Mycosis Fungoides and Response to Intravitreal Methotrexate

Abstract: Intraocular T-cell lymphoma is a rare manifestation of mycosis fungoides and should be considered in the differential diagnosis of chronic uveitis in patients with this history. Intravitreal methotrexate may be an effective adjunctive treatment for this condition.

Cited by 12 publications

References 8 publications

Intraocular T-cell Lymphoma: Clinical Presentation, Diagnosis, Treatment, and Outcome

Intraocular T-cell Lymphoma: Clinical Presentation, Diagnosis, Treatment, and Outcome

Mycosis Fungoides: Analysis of Ophthalmologic Findings in a Series of Cases

Clinical Variability of Ocular Involvement in Mycosis Fungoides

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