Intraocular Pressure in Exfoliation Syndrome

Abstract

A retrospective follow-up study of 206 eyes with exfoliation in 164 patients was carried out. At the time exfoliation (EX) was initially diagnosed, there were 97 patients with unilateral and 42 patients (84 eyes) with bilateral exfoliation. In 25 patients the exfoliation was connected with hypertension or glaucoma in the fellow eye.The average age of the patients with unilateral EX was 66.3 years and that of the patients with bilateral EX 68.0 years. The initial mean IOP ( k S D ) of 17.9 ( & 2.9) mmHg in 97 unilateral EX eyes was statistically significantly higher (2p < 0.001) than in the normal fellow eye 16.1 (k2.5) mmHg.Of the 97 eyes with unilateral EX, 45.3 Yo with an initial mean IOP of 17.4 mmHg remained unchanged. The mean follow-up time was 5.0 years. Conversion of unilateral to bilateral EX was observed in 14.4 Yo of cases. The mean time of conversion was 4.5 years. Of the 84 bilateral EX eyes with an initial mean IOP of 17.0 mmHg, 66.7 Yo remained unchanged.Of the total sample of 206 EX eyes, 65.5 Yo remained normotensive and 34.5 070 developed hypertension or glaucoma during the follow-up period. The initial mean 1OP of those eyes which remained normotensive was statistically significantly lower than that of those which later on developed hypertension or glaucoma (2p<0.001).

The Middle‐Norway eye‐screening study

“…Of the total glaucoma in the respective areas, we found 39.1% capsular in Hi compared to 72.2% in Re, where the PE prevalence is doubled. Similar to Klemetti (1988) roughly 30% of our PE positive persons developed capsular glaucoma, i.e. 26.5%, 27.70/0, 34.5% in Hi, Ho, and Re, respectively.…”

Exfoliation syndrome: prevalence and inheritance in a subisolate of the Finnish population

“…The amount of exfoliation material varies enormously and secondary changes (such as glaucoma) develop for approximately 40% of patients (Klemetti 1988). The amount of exfoliation material varies enormously and secondary changes (such as glaucoma) develop for approximately 40% of patients (Klemetti 1988).…”

Increased intraocular pressure on the first postoperative day following resident-performed cataract surgery

“…PXF is known to be related to ocular hypertension and OAG, [39][40][41] but the relationship to early increased postoperative IOP is controversial. Non-glaucomatous eyes with PXF were reported not to show IOP increase at the postoperative day 1 after sclera tunnel incision and phacoemulsification.…”