Intraocular Juvenile Xantho-Granuloma (Nevoxantho-Endothelioma)*

Sanders, T.E.

doi:10.1016/0002-9394(62)94875-4

Cited by 47 publications

(9 citation statements)

References 11 publications

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“…Lamb and Lain reported the first case of xanthogranuloma with visceral involvement in 1937 (9), This 3-month-old had multiple cutaneous lesions, dyspnea, and fever, and many pulmonary densities on chest radiograph. Subsequently, biopsy-proved lesions have been demonstrated in numerous extracutaneous sites, including the eye, lung, testicle, bone, periosteum, pericardium, myocardium, oropharynx, salivary gland, vulva, skeletal muscle, central nervous system, liver, spleen, and omentum (1,2,(12)(13)(14)(15)(16)(17)(18). Xanthogranulomas have also been associated with a number of systemic disorders, such as urticaria pigmentosa, diabetes mellitus, neurofibromatosis, cytomegalovirus infection, and leukemia (1^22), Although the pathogenesis of xanthogranulomas is unclear, pathologists have suggested a relationship to the histiocytosis X syndromes.…”

Section: Discussionmentioning

confidence: 99%

Xanthogranuloma: Report on Clinical and Histologic Findings in 64 Patients

Cohen

Hood

1989

Pediatric Dermatology

106

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Although xanthogranulomas are frequently encountered by pediatricians and dermatologists, data on the course of this tumor are restricted to several series with limited follow-up. We report on our experience with 64 patients whom we were able to identify from the surgical files. Our data support the currently held view that xanthogranulomas are generally benign, self-limited lesions. They may persist or continue to erupt for years, however, particularly in individuals who develop the first lesion after age 20 years.

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Section: Discussionmentioning

confidence: 99%

Xanthogranuloma: Report on Clinical and Histologic Findings in 64 Patients

Cohen

Hood

1989

Pediatric Dermatology

106

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“…12,13 Hepatic J AM ACAD DERMATOL VOLUME 58, NUMBER 2 involvement may present with hepatomegaly, jaundice, or liver failure. 8 In a review by Dehner 14 of 174 cases of JXG, 3 infants with extracutaneous involvement presented with jaundice, thrombocytopenia, hepatomegaly, and evidence of hepatic failure. Two of the 3 patients died during the first 2 months of life.…”

Section: Discussionmentioning

confidence: 99%

“…The majority of ocular JXGs involve the iris. 8 Other areas of involvement include the episclera, optic nerve, cornea, choroid, and conjunctiva. 9,10 Patients with central nervous system involvement can present with focal neurologic symptoms and physical findings that correlate with the location of the lesions.…”

Section: Discussionmentioning

confidence: 99%

Disseminated juvenile xanthogranulomatosis in a newborn resulting in liver transplantation

Haughton¹,

Horii

Shao

et al. 2008

Journal of the American Academy of Dermatology

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“…JXG has been found involving lhe eye (9), lung (2,4,5,6,8), epicardium (12), liver (2) and lesticle (5,8). Several eases have been treated by radiolherapy, notably the friable eye lesions whirh may lead lo sigmfieanl anlerior ehamber bleeding before resolution oeeurs (9,12). II \\'ould appear that involulion is the nalural course of lhe deep sealed and rutaneous lesions.…”

Section: Discussioßmentioning

confidence: 97%