Intraocular biopsy in uveitis

Patnaik, Gazal; Annamalai, Radha; Biswas, Jyotirmay

doi:10.4103/ijo.ijo_1325_20

Cited by 6 publications

(2 citation statements)

References 51 publications

(30 reference statements)

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“…In some cases, biopsy of both ocular and other tissues may be required to provide a definite diagnosis. 16 Intraocular biopsy is a histopathologic or cytologic evaluation of surgically obtained specimens, such as the aqueous or vitreous humor, retinal fluid, and tissues such as the iris, retina, and choroid. Current biopsy techniques have contributed significantly to the decision-making.…”

Section: Discussionmentioning

confidence: 99%

The Large Hellenic Study of Uveitis: Diagnostic and Therapeutic Algorithms, Complications, and Final Outcome

Kalogeropoulos

Asproudis

Stefaniotou

et al. 2023

Asia-Pacific Journal of Ophthalmology

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Purpose: The purpose of this study is to present the diagnostic and therapeutic algorithms, complications, and final outcome in the management of uveitic patients at a tertiary academic referral center. Design: Observational study. Methods: Analysis of the archives of 6191 uveitic patients at the Ocular Inflammation Service of the Department of Ophthalmology of the University Hospital of Ioannina in Greece from 1991 to 2020. Results: During the 30 years of the study, the diagnostic ability climbed from 45.43% (1991–1995) to 73.4% (2016–2020). This improvement was linked to several factors including the increase in the number of diagnostic paracenteses for the analysis of intraocular fluids, the range and quality of laboratory blood tests, the multimodal ophthalmic imaging, the proper use of nonophthalmic imaging, and the multidisciplinary approach. The degree of uveitis-related complications was related to the severity and cause of inflammation, the recurrence rate, inappropriate treatment, and the prolonged or initially inactive inflammation. The 3 most common complications included cataract, macular edema, and glaucoma. Apart from the modern treatments and surgical techniques, the 3-month preoperative control of inflammation played a critical role in the surgical outcomes. The percentage of patients with a successful outcome increased from 72% (2001–2005) to 90.50% (2016–2020). The center’s experience, prompt referral, patient’s compliance, and regular follow-ups are associated with a better outcome. The analysis of the results allowed the development of diagnostic and therapeutic algorithms. Conclusions: Developing diagnostic and therapeutic algorithms allows for the efficient management of uveitis, leading to better visual outcome and therefore a better quality of life.

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Section: Discussionmentioning

confidence: 99%

The Large Hellenic Study of Uveitis: Diagnostic and Therapeutic Algorithms, Complications, and Final Outcome

Kalogeropoulos

Asproudis

Stefaniotou

et al. 2023

Asia-Pacific Journal of Ophthalmology

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“…The issue begins with a beautiful account of the history and evolution of the USI, pays tribute to the pioneers of uveitis practice in India, and then moves on to many different forms of uveitis and scleritis. [ 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 ]…”

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confidence: 99%