Fortschr Röntgenstr

1993

DOI: 10.1055/s-2008-1032749

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Intramedullary spinal cord germinoma

Kaoru Hanafusa¹,

Hidenori Shibuya²,

Mitsuyuki Abe³

et al.

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Cited by 26 publications

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Rare Spinal Cord Tumors

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et al. 2019

Spinal Cord Tumors

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No abstract

Rare Spinal Cord Tumors

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et al. 2019

Spinal Cord Tumors

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Intramedullary spinal cord germinoma expresses the protooncogene c-kit

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et al. 2005

Acta Neurochir (Wien)

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A 33-year-old woman first noticed numbness in the both lower extremities and the numbness gradually extended up to the thorax. Magnetic resonance (MR) imaging demonstrated a mass with moderate and heterogeneous enhancement and peritumoural intramedullary cysts in the spinal cord at the T-1 to T-3 levels. The tumour was explored partially and intra-operative pathological examination demonstrated the so-called "two-cell pattern" typical of germinoma. The margin of the tumour was not clear. Histological examination showed germinoma with strong c-kit protein expression on the tumour cell surface. Chemotherapy and radiation therapy were given following surgery. Her neurological deficits were improved but not resolved.

Spinal intradural primary germ cell tumour—review of literature and case report

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et al. 2009

Acta Neurochir (Wien)

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Limited surgery followed by upfront radiation therapy and adjuvant chemotherapy is the optimal management of this rare group of tumour. Omission of radiation therapy from the treatment armamentarium might engender local recurrence and spinal dissemination at first failure.

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